Journal article
Nuclear Imaging of Neuroendocrine Tumors
Surgical oncology clinics of North America, Vol.29(2), pp.209-221
04/01/2020
DOI: 10.1016/j.soc.2019.11.007
PMCID: PMC7700750
PMID: 32151356
Abstract
Consensus guidelines acknowledge the role of gallium Ga-68 (Ga-68) 1,4,7,10-tetraazacyclododecane-N,N',N '',N'''-tetraacetic (DOTA) somatostatin receptor (SSTR) positron emission tomography/computed tomography (PET/CT) in management of neuroendocrine tumor (NET) patients. Ga-68-DOTA-SSTR PET/CT demonstrates superior performance to conventional imaging in initial detection, staging, detection of recurrent tumor, and detection of unknown primary in known metastatic disease. Ga-68-DOTA-SSTR PET/CT is low yield for NET detection in the setting of symptoms or elevated biomarkers when conventional imaging is negative, but may still guide management. The role of Ga-68-DOTA-SSTR PET/CT is not established in monitoring response to systemic therapy but may identify progression through detection of new metastases.
Details
- Title: Subtitle
- Nuclear Imaging of Neuroendocrine Tumors
- Creators
- Janet Pollard - Department of Radiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA. Electronic address: janet-pollard@uiowa.edu.Parren McNeely - Roy J. and Lucille A. Carver College of MedicineYusuf Menda - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- Surgical oncology clinics of North America, Vol.29(2), pp.209-221
- DOI
- 10.1016/j.soc.2019.11.007
- PMID
- 32151356
- PMCID
- PMC7700750
- NLM abbreviation
- Surg Oncol Clin N Am
- ISSN
- 1055-3207
- eISSN
- 1558-5042
- Publisher
- Elsevier
- Number of pages
- 14
- Grant note
- P50 CA174521 / NCI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
- Language
- English
- Date published
- 04/01/2020
- Academic Unit
- Radiology; Radiation Oncology
- Record Identifier
- 9984313070902771
Metrics
8 Record Views