Journal article
Nuclear egress of herpesviruses
Virologica Sinica, Vol.23(6), pp.406-415
12/08/2008
DOI: 10.1007/s12250-008-3004-1
Abstract
Herpesviruses assemble and fill their capsids in the infected cell nucleus, and must then move this enormous macromolecular assembly across the nuclear membrane and into the cytoplasm. Doing so is a complex, multi-step process that involves envelopment of the capsid at the inner nuclear membrane and de-envelopment by fusion with the outer nuclear membrane. This process is orchestrated by viral proteins, but requires the modification of cellular structures and mechanisms including the nuclear lamina. In this review I summarize recent research on the mechanism of nuclear envelopment and the viral and cellular systems involved in its execution.
Details
- Title: Subtitle
- Nuclear egress of herpesviruses
- Creators
- Richard J. Roller - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Virologica Sinica, Vol.23(6), pp.406-415
- Publisher
- SP Wuhan Institute of Virology, CAS
- DOI
- 10.1007/s12250-008-3004-1
- ISSN
- 1674-0769
- eISSN
- 1995-820X
- Language
- English
- Date published
- 12/08/2008
- Academic Unit
- Microbiology and Immunology
- Record Identifier
- 9984297424302771
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