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Nucleotide Sequence, Chromosome Localization, and Evolutionary Conservation of a Serine Hydroxymethyltransferase-Processed Pseudogene
Journal article   Peer reviewed

Nucleotide Sequence, Chromosome Localization, and Evolutionary Conservation of a Serine Hydroxymethyltransferase-Processed Pseudogene

E. J. Devor and R. M. Dill-Devor
Human heredity, Vol.47(3), pp.125-130
05/01/1997
DOI: 10.1159/000154400
PMID: 09156323

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Abstract

The nucleotide sequence and chromosomal localization of a human pseudogene is reported. Sequence data suggest that this pseudogene was derived via reverse transcription from the gene encoding the cytosolic isoform of the enzyme serine hydroxymethyltransferase. In addition, a heteroduplex analysis of this pseudogene among several species of nonhuman primate indicates a relatively high degree of sequence conservation.
Obstetrics and Gynecology

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