Journal article
Objective Test of Cochlear Dead Region: Electrophysiologic Approach using Acoustic Change Complex
Scientific reports, Vol.8(1), 3645
02/26/2018
DOI: 10.1038/s41598-018-21754-7
PMCID: PMC5832147
PMID: 29483598
Abstract
The goal of this study was to develop an objective and neurophysiologic method of identifying the presence of cochlear dead region (CDR) by combining acoustic change complex (ACC) responses with threshold-equalizing noise (TEN) test. The goal of the first study was to confirm whether ACC could be evoked with TEN stimuli and to also optimize the test conditions. The goal of the second study was to determine whether the TEN-ACC test is capable of detecting CDR(s). The ACC responses were successfully recorded from all study participants. Both behaviorally and electrophysiologically obtained masked thresholds (TEN threshold and TEN-ACC threshold) were similar and below 10 and 12 dB SNR in NH listeners, respectively. HI listeners were divided into HI (non-CDR) and CDR groups based on the behavioral TEN test. For the non-CDR group, TEN-ACC thresholds were below 12 dB which were similar to NH listeners. However, for the CDR group, TEN-ACC thresholds were significantly higher (≥12 dB SNR) than those in the NH and HI groups, indicating that CDR(s) can be objectively detected using the ACC. Results of this study demonstrate that it is possible to detect the presence of CDR using an electrophysiologic method.
Details
- Title: Subtitle
- Objective Test of Cochlear Dead Region: Electrophysiologic Approach using Acoustic Change Complex
- Creators
- Soojin Kang - School of Electrical Engineering, Biomedical Engineering, University of Ulsan, Ulsan, KoreaJihwan Woo - School of Electrical Engineering, Biomedical Engineering, University of Ulsan, Ulsan, KoreaHeesung Park - Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaCarolyn J Brown - Departments of Speech Pathology and Audiology, University of Iowa, Iowa City, Iowa, USASung Hwa Hong - Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea. hongsh@skku.eduIl Joon Moon - Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. moonij@skku.edu
- Resource Type
- Journal article
- Publication Details
- Scientific reports, Vol.8(1), 3645
- DOI
- 10.1038/s41598-018-21754-7
- PMID
- 29483598
- PMCID
- PMC5832147
- NLM abbreviation
- Sci Rep
- ISSN
- 2045-2322
- eISSN
- 2045-2322
- Publisher
- England
- Language
- English
- Date published
- 02/26/2018
- Academic Unit
- Communication Sciences and Disorders; Otolaryngology
- Record Identifier
- 9984002498802771
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