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Obstructive Jaundice as the Initial Manifestation of Gastric Adenocarcinoma
Journal article   Open access   Peer reviewed

Obstructive Jaundice as the Initial Manifestation of Gastric Adenocarcinoma

Shehbaz M Ansari, Dhrumil Patel, Yashant Aswani, Abhishek Bairy and Hiba Narvel
Curēus (Palo Alto, CA), Vol.14(12)
12/13/2022
DOI: 10.7759/cureus.32478
PMCID: PMC9835852
PMID: 36644047
url
https://doi.org/10.7759/cureus.32478View
Published (Version of record) Open Access

Abstract

A 52-year-old female presented with epigastric pain, yellowing of the sclera, and vomiting for three weeks. Laboratory investigations revealed markedly elevated serum bilirubin and alkaline phosphatase levels, accompanied by a modest rise in transaminases. A clinical diagnosis of obstructive jaundice was established. Ultrasound of the abdomen depicted a mass in the region of the head of the pancreas. Contrast-enhanced computed tomography (CECT) of the abdomen revealed an infiltrative gastric mass spreading across the gastroduodenal junction and involving the ampulla of Vater. Owing to comorbid conditions and widespread lymphadenopathy, a palliative gastrojejunostomy with excision biopsy was performed. Histopathology confirmed an undifferentiated gastric adenocarcinoma.

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