Journal article
Occipital bending (Yakovlevian torque) in bipolar depression
Psychiatry research. Neuroimaging, Vol.231(1), pp.8-14
01/30/2015
DOI: 10.1016/j.pscychresns.2014.11.008
PMID: 25480522
Abstract
Differing levels of occipital lobe asymmetry and enlarged lateral ventricles have been reported within patients with bipolar disorder (BD) compared with healthy controls, suggesting different rates of occipital bending (OB). This may exert pressure on subcortical structures, such as the hippocampus, reduced among psychiatric patients. We investigated OB prevalence in 35 patients with BD and 36 healthy controls, and ventricular and occipital volumes. Prevalence was four Limes higher among BD patients (12/35 [34.3%]) than in control subjects (3/36 [8.3%]), as well as larger lateral ventricular volumes (LVVs). Furthermore, we found OB to relate to left-to-right ventricular and occipital lobe volume (OLV) ratios. Those with OB also had reduced left-to-right hippocampal volume ratios. The results suggest that OB is more common among BD patients than healthy subjects, and prevalent in both BD Type l and Type II patients. We posit that anomalies in neural pruning or ventricular enlargement may precipitate OB, consequently resulting in one occipital lobe twisting around the other Although the clinical implications of these results are unclear, the study suggests that asymmetrical ventricular volume matched with a pattern of oppositely asymmetrical occipital volume is related to OB and may be a marker of psychiatric illness. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
Details
- Title: Subtitle
- Occipital bending (Yakovlevian torque) in bipolar depression
- Creators
- Jerome J. Maller - Monash Alfred Psychiatry Research centreRodney Anderson - Monash UniversityRichard H. Thomson - Monash Alfred Psychiatry Research centreJeffrey V. Rosenfeld - Monash UniversityZafiris J. Daskalakis - Centre for Addiction and Mental HealthPaul B. Fitzgerald - Monash Alfred Psychiatry Research centre
- Resource Type
- Journal article
- Publication Details
- Psychiatry research. Neuroimaging, Vol.231(1), pp.8-14
- DOI
- 10.1016/j.pscychresns.2014.11.008
- PMID
- 25480522
- NLM abbreviation
- Psychiatry Res Neuroimaging
- ISSN
- 0925-4927
- eISSN
- 1872-7506
- Publisher
- Elsevier
- Number of pages
- 7
- Grant note
- 6069070 / NHMRC Practitioner Fellowship; National Health & Medical Research Council (NHMRC) of Australia
- Language
- English
- Date published
- 01/30/2015
- Academic Unit
- Radiology
- Record Identifier
- 9984848501502771
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