Occult Primary Neuroendocrine Tumor Metastasis to the Breast Detected on Screening Mammogram

Fabiana Policeni; Brittany Pakalniskis; Limin Yang

doi:10.4103/2156-7514.191439

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Occult Primary Neuroendocrine Tumor Metastasis to the Breast Detected on Screening Mammogram

Journal article

Open access

Occult Primary Neuroendocrine Tumor Metastasis to the Breast Detected on Screening Mammogram

Fabiana Policeni, Brittany Pakalniskis and Limin Yang

Journal of clinical imaging science, Vol.6(3), p.41

07/01/2016

DOI: 10.4103/2156-7514.191439

PMCID: PMC5070031

PMID: 27761301

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Abstract

Metastatic tumors are rare in the breast. Well-differentiated neuroendocrine tumors (WDNETs) are slow-growing neoplasms that arise from neuroendocrine cells, particularly in the gastrointestinal tract and bronchial tree. Metastatic WDNET to the breast is a rare entity. We present a case report of ileal WDNET metastatic to the breast which was initially identified as a small mass in the patient's left breast on screening mammography. Targeted ultrasound identified a suspicious mass, and ultrasound-guided percutaneous core biopsy was performed. Pathology revealed metastatic WDNET. Breast magnetic resonance imaging (MRI) was then performed and demonstrated left axillary Level 2 lymphadenopathy, and liver lesions were suspicious for metastasis. The patient underwent abdominal computed tomography (CT) to evaluate for distant metastatic disease. A spiculated mass was found near the ileocecal valve, suggestive of primary ileal WDNET. In addition, CT identified multiple liver lesions, most compatible with metastasis. Indium 111 OctreoScan confirmed radiotracer uptake in the ileum consistent with primary neuroendocrine tumor. In this report, we review the imaging characteristics of metastatic WDNET to the breast by different imaging modalities including mammogram, ultrasound, and breast MRI.

neuroendocrine tumor

breast metastasis

Breast imaging

Case Report

Details

Title: Subtitle: Occult Primary Neuroendocrine Tumor Metastasis to the Breast Detected on Screening Mammogram
Creators: Fabiana Policeni - Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
Brittany Pakalniskis - Department of Pathology, University of Washington, Seattle, WA, USA
Limin Yang - Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
Resource Type: Journal article
Publication Details: Journal of clinical imaging science, Vol.6(3), p.41
DOI: 10.4103/2156-7514.191439
PMID: 27761301
PMCID: PMC5070031
NLM abbreviation: J Clin Imaging Sci
ISSN: 2156-7514
eISSN: 2156-5597
Publisher: Medknow Publications & Media Pvt Ltd; India
Language: English
Date published: 07/01/2016
Academic Unit: Radiology
Record Identifier: 9984051780702771

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