Journal article
Occupation and Semen Parameters in a Cohort of Fertile Men
Journal of occupational and environmental medicine, Vol.64(10), pp.831-838
10/01/2022
DOI: 10.1097/JOM.0000000000002607
PMCID: PMC9529786
PMID: 35902368
Abstract
Objective We examined associations between occupation and semen parameters in demonstrably fertile men in the Study for Future Families. Methods Associations of occupation and workplace exposures with semen volume, sperm concentration, motility, and morphology were assessed using generalized linear modeling. Results Lower sperm concentration and motility were seen in installation, maintenance, and repair occupations. Higher exposure to lead, and to other toxicants, was seen in occupations with lower mean sperm concentrations (prevalence ratio for lead: 4.1; pesticides/insecticides: 1.6; solvents: 1.4). Working with lead for more than 3 months was associated with lower sperm concentration, as was lead exposure outside of work. Conclusions We found evidence in demonstrably fertile men for reduced sperm quality with lead, pesticide/herbicide, and solvent exposure. These results may identify occupations where protective measures against male reproductive toxicity might be warranted.
Details
- Title: Subtitle
- Occupation and Semen Parameters in a Cohort of Fertile Men
- Creators
- John D. Meyer - Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, 1 Gustave L Levy Pl,Box 1057, New York, NY 10029 USACharlene Brazil - Univ Calif Davis, Dept Obstet & Gynecol, Davis, CA USAJ. Bruce Redmon - Univ Minnesota, Sch Med, Dept Med, Minneapolis, MN 55455 USAChristina Wang - Univ Calif Los Angeles, David Geffen Sch Med, Harbor UCLA Med Ctr, Div Endocrinol, Torrance, CA USAAmy E. Sparks - University of IowaShanna H. Swan - Icahn Sch Med Mt Sinai, Dept Environm Med & Publ Hlth, 1 Gustave L Levy Pl,Box 1057, New York, NY 10029 USA
- Resource Type
- Journal article
- Publication Details
- Journal of occupational and environmental medicine, Vol.64(10), pp.831-838
- DOI
- 10.1097/JOM.0000000000002607
- PMID
- 35902368
- PMCID
- PMC9529786
- NLM abbreviation
- J Occup Environ Med
- ISSN
- 1076-2752
- eISSN
- 1536-5948
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 8
- Grant note
- Centers for Disease Control and Prevention/National Institute for Occupational Safety OH011540; ES09916 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Language
- English
- Date published
- 10/01/2022
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9984318221202771
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