Occupational Physical Activity and Coronary Heart Disease in Women’s Health Initiative Observational Study

Conglong Wang; Anneclaire J De Roos; Kaori Fujishiro; Matthew A Allison; Robert Wallace; Rebecca A Seguin; Rami Nassir; Yvonne L Michael

doi:10.1093/gerona/gly288

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Occupational Physical Activity and Coronary Heart Disease in Women’s Health Initiative Observational Study

Journal article

Open access

Peer reviewed

Occupational Physical Activity and Coronary Heart Disease in Women’s Health Initiative Observational Study

Conglong Wang, Anneclaire J De Roos, Kaori Fujishiro, Matthew A Allison, Robert Wallace, Rebecca A Seguin, Rami Nassir and Yvonne L Michael

The journals of gerontology. Series A, Biological sciences and medical sciences, Vol.74(12), pp.1952-1958

12/24/2018

DOI: 10.1093/gerona/gly288

PMCID: PMC6853693

PMID: 30590438

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Abstract

Background: Women comprise nearly half of the labor force in our society, but the impact of the occupational psychical activity on women's heart health in later life was unclear. We conducted a case-cohort study to assess the association of occupational physical activity (OPA), alone and jointly with leisure-time physical activity (LTPA) and risk of coronary heart disease (CHD). Methods: We included women enrolled in Women's Health Initiative Observational Study who provided an occupational history at baseline and were followed until 2013 for the first occurrence of myocardial infarction or death from CHD (mean age ± SD = 63.4 ± 7.2). A total of 5,243 women free of CHD at baseline were randomly selected into a subcohort and 3,421 CHD events were adjudicated during follow-up. Through linkage of Standard Occupational Classification codes to the Occupational Information Network, we assessed cumulative and most recent exposure of OPA. LTPA was assessed through Women's Health Initiative's physical activity questionnaire. Weighted Cox proportional hazard models were used to evaluate CHD risk. Results: After adjustment for demographic and socioeconomic factors, levels of OPA were not associated with CHD risk. Compared with women with low OPA and high LTPA, women with moderate to high cumulative OPA and low LTPA had relative high CHD risk (hazard ratio [HR]: 1.54, 95% confidence interval [CI]: 1.26, 1.88 for moderate OPA and HR: 1.46. 95% CI: 1.20, 1.78 for high OPA). Discussion: Results from this study suggest no overall association between lifetime OPA and CHD risk in women, but the impact of OPA varies by LTPA levels.

Cardiovascular Disease

Leisure time

Lifetime

Medical Sciences

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The Journal of Gerontology

Details

Title: Subtitle: Occupational Physical Activity and Coronary Heart Disease in Women’s Health Initiative Observational Study
Creators: Conglong Wang - Drexel University
Anneclaire J De Roos - Drexel University
Kaori Fujishiro - National Institute for Occupational Safety and Health
Matthew A Allison - University of California System
Robert Wallace - University of Iowa
Rebecca A Seguin - Cornell University
Rami Nassir - University of California, Davis
Yvonne L Michael - Drexel University
Resource Type: Journal article
Publication Details: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol.74(12), pp.1952-1958
DOI: 10.1093/gerona/gly288
PMID: 30590438
PMCID: PMC6853693
NLM abbreviation: J Gerontol A Biol Sci Med Sci
ISSN: 1079-5006
eISSN: 1758-535X
Publisher: Oxford University Press
Grant note: ; ; ; HHSN268201600018C; HHSN268201600001C; HHSN268201600002C; HHSN268201600003C; HHSN268201600004C / ; ; ;
Language: English
Date published: 12/24/2018
Academic Unit: Epidemiology; Injury Prevention Research Center; Internal Medicine
Record Identifier: 9984363640202771

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