Office-Based Photoangiolytic Laser Treatment of Reinke's Edema: Safety and Voice Outcomes

Ian J Koszewski; Matthew R Hoffman; W Greg Young; Ying-Ta Lai; Seth H Dailey

doi:10.1177/0194599815577104

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Office-Based Photoangiolytic Laser Treatment of Reinke's Edema: Safety and Voice Outcomes

Journal article

Peer reviewed

Office-Based Photoangiolytic Laser Treatment of Reinke's Edema: Safety and Voice Outcomes

Ian J Koszewski, Matthew R Hoffman, W Greg Young, Ying-Ta Lai and Seth H Dailey

Otolaryngology-head and neck surgery, Vol.152(6), pp.1075-1081

06/2015

DOI: 10.1177/0194599815577104

PMID: 25820581

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Abstract

To evaluate the safety, tolerability, and voice outcomes of office-based photoangiolytic laser treatment of Reinke's edema. Case series with chart review. Academic medical center. We performed a retrospective analysis of patients undergoing office-based laser treatment of endoscopy-proven Reinke's edema. Safety and tolerability were evaluated by reviewing complications. Voice outcomes were analyzed by comparing pre- and postprocedural acoustic, aerodynamic, and Voice Handicap Index measurements. Complete data sets were not available for all subjects; sample size for each parameter is reported with the corresponding result. Nineteen patients met inclusion criteria. There were no minor or major complications. Five procedures were truncated due to patient intolerance. Phonatory frequency range increased (n = 12, P = .003), while percent jitter decreased (n = 12, P = .004). Phonation threshold pressure decreased after treatment (n = 4, P = .049). Voice Handicap Index also decreased (n = 14, P < .001). This study represents the largest series of patients undergoing office-based photoangiolytic laser treatment specifically for Reinke's edema. Our data suggest that this is a safe and effective modality to treat dysphonia associated with Reinke's edema, although patient intolerance of the procedure may represent a barrier.

Adult

Aged

Ambulatory Surgical Procedures - methods

Cohort Studies

Female

Follow-Up Studies

Humans

Intraoperative Complications

Laryngeal Edema - diagnosis

Laryngeal Edema - surgery

Laryngoscopy - methods

Laser Therapy - methods

Male

Middle Aged

Patient Safety

Retrospective Studies

Risk Assessment

Statistics, Nonparametric

Treatment Outcome

Vocal Cords - injuries

Voice Quality

Details

Title: Subtitle: Office-Based Photoangiolytic Laser Treatment of Reinke's Edema: Safety and Voice Outcomes
Creators: Ian J Koszewski - University of Wisconsin–Madison
Matthew R Hoffman - University of Wisconsin School of Medicine and Public Health
W Greg Young - University of Wisconsin School of Medicine and Public Health
Ying-Ta Lai - University of Wisconsin–Madison
Seth H Dailey - University of Wisconsin–Madison
Resource Type: Journal article
Publication Details: Otolaryngology-head and neck surgery, Vol.152(6), pp.1075-1081
DOI: 10.1177/0194599815577104
PMID: 25820581
ISSN: 0194-5998
eISSN: 1097-6817
Language: English
Date published: 06/2015
Academic Unit: Otolaryngology
Record Identifier: 9984366380302771

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