Journal article
Oil-water biphasic parallel flow for the precise patterning of metals and cells
Biomedical microdevices, Vol.16(2), pp.245-253
04/01/2014
DOI: 10.1007/s10544-013-9828-y
PMID: 24337429
Abstract
Fluidic patterning is a convenient and versatile tool for the patterning of materials, cells and microstructures on surface and in microchannels. However, its performance is usually limited by transverse diffusion between fluid streams. It would blur the boundary and deteriorate the precision of patterns. In this paper, we adopted geometric confinement to generate biphasic parallel flow that is constituted of oil and water. Since there is minimum transverse diffusion in biphasic parallel flow, the performance of fluid patterning is expected to be improved. The results show that the metal (Silver and Chromium) patterns have distinct boundary and well-controlled geometry in comparison with that by conventional laminar flow patterning. Furthermore, the high biocompatibility of oil phase (perfluorodecalin, PFD) enables the precise patterning of viable bacteria inside microchannels. Our work demonstrated a new route of using biphasic parallel flow to patterning, which would serve wide applications in prototyping and research settings.
Details
- Title: Subtitle
- Oil-water biphasic parallel flow for the precise patterning of metals and cells
- Creators
- Xuan Mu - Chinese Academy of Medical Sciences & Peking Union Medical CollegeQionglin Liang - Tsinghua UniversityJun Zhou - Chinese Academy of Medical Sciences & Peking Union Medical CollegeKangning Ren - Tsinghua UniversityPing Hu - East China University of Science and TechnologyYiming Wang - Tsinghua UniversityZhi Zheng - Chinese Academy of Medical Sciences & Peking Union Medical CollegeGuoan Luo - Tsinghua University
- Resource Type
- Journal article
- Publication Details
- Biomedical microdevices, Vol.16(2), pp.245-253
- Publisher
- Springer Nature
- DOI
- 10.1007/s10544-013-9828-y
- PMID
- 24337429
- ISSN
- 1387-2176
- eISSN
- 1572-8781
- Number of pages
- 9
- Grant note
- 21305162; 21235004; 21175080 / National Natural Science Foundation of China; National Natural Science Foundation of China (NSFC) 2013ZX09507005 / National Science and Technology Major Project of China Importation and Development of High-Caliber Talents Project of Beijing Municipal Institutions
- Language
- English
- Date published
- 04/01/2014
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984277459302771
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