Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa

Henry A Adeola; Olujide O Soyele; Anthonio O Adefuye; Sikiru A Jimoh; Azeez Butali

doi:10.1186/s12935-017-0432-8

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Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa

Journal article

Open access

Peer reviewed

Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa

Henry A Adeola, Olujide O Soyele, Anthonio O Adefuye, Sikiru A Jimoh and Azeez Butali

Cancer cell international, Vol.17(1), pp.61-61

06/05/2017

DOI: 10.1186/s12935-017-0432-8

PMCID: PMC5460491

PMID: 28592923

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Abstract

Background: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and "big data" processing have contributed immensely to individualized/personalized medicine in the developed world. Main body: At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratification of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the proficiency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among different human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences. Conclusion: In this review, we examined the challenges and prospects of using currently available omics-based technologies vis-à-vis oral pathology as well as prompt cancer diagnosis and treatment in a resource limited setting.

Oral pathology

Review

Molecular

Omics-based

Challenges

Developing world

Details

Title: Subtitle: Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa
Creators: Henry A Adeola - Cape Town, South Africa
Olujide O Soyele - Ile-Ife, Nigeria
Anthonio O Adefuye - Bloemfontein, South Africa
Sikiru A Jimoh - Mthatha, Eastern Cape South Africa
Azeez Butali - Iowa City, IA USA
Resource Type: Journal article
Publication Details: Cancer cell international, Vol.17(1), pp.61-61
DOI: 10.1186/s12935-017-0432-8
PMID: 28592923
PMCID: PMC5460491
NLM abbreviation: Cancer Cell Int
ISSN: 1475-2867
eISSN: 1475-2867
Publisher: BioMed Central; London
Grant note: DE022378-04 / ; 72429 / ;
Language: English
Date published: 06/05/2017
Academic Unit: Oral Pathology, Radiology and Medicine; Stead Family Department of Pediatrics; Craniofacial Anomalies Research Center; Dental Research
Record Identifier: 9984065703102771

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