Journal article
On PAR with aPC to target inflammasomes
Blood, Vol.130(24), pp.2579-2581
12/14/2017
DOI: 10.1182/blood-2017-09-806307
PMID: 29242206
Abstract
In this issue of Blood, Nazir et al demonstrate that activated protein C (aPC) protects from ischemia-reperfusion injury by suppressing the activation of NLRP3 inflammasomes, revealing a novel target of the anti-inflammatory pathway triggered by biased agonism of proteinase-activated receptor 1 (PAR-1).(1)
Details
- Title: Subtitle
- On PAR with aPC to target inflammasomes
- Creators
- Steven R. Lentz - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Blood, Vol.130(24), pp.2579-2581
- Publisher
- Amer Soc Hematology
- DOI
- 10.1182/blood-2017-09-806307
- PMID
- 29242206
- ISSN
- 0006-4971
- eISSN
- 1528-0020
- Number of pages
- 5
- Language
- English
- Date published
- 12/14/2017
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984359859502771
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