Oncogenic osteomalacia presenting as bilateral stress fractures of the tibia

K Ohashi; Takeshi Ohnishi; Tohru Ishikawa; Haruo Tani; Keisuke Uesugi; Masayuki Takagi

doi:10.1007/s002560050471

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$Oncogenic osteomalacia presenting as bilateral stress fractures of the tibia$

Journal article

Peer reviewed

Oncogenic osteomalacia presenting as bilateral stress fractures of the tibia

K Ohashi, Takeshi Ohnishi, Tohru Ishikawa, Haruo Tani, Keisuke Uesugi and Masayuki Takagi

Skeletal radiology, Vol.28(1), pp.46-48

01/1999

DOI: 10.1007/s002560050471

PMID: 10068075

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Abstract

We report on a patient with bilateral stress fractures of the tibia who subsequently showed classic biochemical features of oncogenic osteomalacia. Conventional radiographs were normal. MR imaging revealed symmetric, bilateral, band-like low-signal lesions perpendicular to the medial cortex of the tibiae and corresponding to the only lesions subsequently seen on the bone scan. A maxillary sinus lesion was subsequently detected and surgically removed resulting in prompt alleviation of symptoms and normalization of hypophosphatemia and low 1,25-(OH)2 vitamin D3. The lesion was pathologically diagnosed as a hemangiopericytoma-like tumor. Patients with oncogenic osteomalacia may present with stress fractures limited to the tibia, as seen in athletes. The clue to the real diagnosis lies in paying close attention to the serum phosphate levels, especially in patients suffering generalized symptoms of weakness and not given to unusual physical activity.

Tibia-stress fractures

Osteomalacia

Maxillary sinus

tumor-induced

Details

Title: Subtitle: Oncogenic osteomalacia presenting as bilateral stress fractures of the tibia
Creators: K Ohashi - Department of Radiology, St. Marianna University Hospital, 2–16–1 Sugao Miyamae-ku, Kawasaki City, Kanagawa, Japan 216 JP
Takeshi Ohnishi - Department of Radiology, St. Marianna University Hospital, 2–16–1 Sugao Miyamae-ku, Kawasaki City, Kanagawa, Japan 216 JP
Tohru Ishikawa - Department of Radiology, St. Marianna University Hospital, 2–16–1 Sugao Miyamae-ku, Kawasaki City, Kanagawa, Japan 216 JP
Haruo Tani - Department of Internal Medicine III, St. Marianna University Hospital, Kawasaki City, Kanagawa, Japan JP
Keisuke Uesugi - Department of Otolaryngology, St. Marianna University Hospital, Kawasaki City, Kanagawa, Japan JP
Masayuki Takagi - Department of Pathology, St. Marianna University Hospital, Kawasaki City, Kanagawa, Japan JP
Resource Type: Journal article
Publication Details: Skeletal radiology, Vol.28(1), pp.46-48
Publisher: Springer-Verlag; Berlin/Heidelberg
DOI: 10.1007/s002560050471
PMID: 10068075
ISSN: 0364-2348
eISSN: 1432-2161
Language: English
Date published: 01/1999
Academic Unit: Radiology
Record Identifier: 9984051876402771

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