Journal article
One-year clinical outcomes of protected and unprotected left main coronary artery stenting
European heart journal, Vol.24(17), pp.1554-1559
09/01/2003
DOI: 10.1016/S0195-668X(03)00314-2
PMID: 12927190
Abstract
Aims To evaluate outcomes for left main coronary artery (LMCA) stenting and compare results between protected (left coronary grafted) and unprotected LMCA stenting in the current bare-metal stent era. Methods We reviewed outcomes among 142 consecutive patients who underwent protected or unprotected LMCA stenting since 1997. All-cause mortality, myocardial infarction (MI), target-lesion revascularization (TLR), and the combined majoradverse clinical event (MACE) rates at one year were computed. Results Ninety-nine patients (70%) underwent protected and 43 patients (30%) underwent unprotected LMCA stenting. In the unprotected group, 86% were considered poor surgical candidates. Survival at one year was 88% for all patients, TLR 20%, and MACE 32%. At one year, survival was reduced in the unprotected group (72% vs. 95%, P<0.001) and MACE was increased in the unprotected patients (49% vs. 25%, P=0.005). Conclusions In the current era, stenting for both protected and unprotected LMCA disease is still associated with high long-term mortality and MACE rates. Stenting for unprotected LMCA disease in a high-risk population should only be considered in the absence of other revascularization options. Further studies are needed to evaluate the role of stenting for unprotected LMCA disease.
Details
- Title: Subtitle
- One-year clinical outcomes of protected and unprotected left main coronary artery stenting
- Creators
- Michael P Kelley - University of Pennsylvania Health System, Philadelphia, PA, USABruce D Klugherz - University of Pennsylvania Health System, Philadelphia, PA, USASeyed M Hashemi - University of Pennsylvania Health System, Philadelphia, PA, USANicolas F Meneveau - Hôpital Jean Minjoz,Besancon, FranceJanet M Johnston - University of Pittsburgh, Pittsburgh, PA, USAWilliam H Matthai - University of Pennsylvania Health System, Philadelphia, PA, USAVidya S Banka - University of Pennsylvania Health System, Philadelphia, PA, USAHoward C Herrmann - University of Pennsylvania Health System, Philadelphia, PA, USAJohn W Hirshfeld - University of Pennsylvania Health System, Philadelphia, PA, USAStephen E Kimmel - University of Pennsylvania Health System, Philadelphia, PA, USADaniel M Kolansky - University of Pennsylvania Health System, Philadelphia, PA, USAPhillip A Horwitz - University of Pennsylvania Health System, Philadelphia, PA, USAFrancois Schiele - Hôpital Jean Minjoz,Besancon, FranceJean-Pierre L Bassand - Hôpital Jean Minjoz,Besancon, FranceRobert L Wilensky - University of Pennsylvania Health System, Philadelphia, PA, USA
- Resource Type
- Journal article
- Publication Details
- European heart journal, Vol.24(17), pp.1554-1559
- Publisher
- Oxford University Press
- DOI
- 10.1016/S0195-668X(03)00314-2
- PMID
- 12927190
- ISSN
- 0195-668X
- eISSN
- 1522-9645
- Language
- English
- Date published
- 09/01/2003
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984094676902771
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