Journal article
One-year outcomes from a prospective, randomized, eye-to-eye comparison of wavefront-guided and wavefront-optimized LASIK in myopes
Ophthalmology (Rochester, Minn.), Vol.120(12), pp.2396-2402
12/2013
DOI: 10.1016/j.ophtha.2013.05.010
PMID: 23778091
Abstract
To compare wavefront (WF)-guided and WF-optimized LASIK in myopes.
Prospective, randomized, eye-to-eye study.
A total of 72 eyes of 36 participants with myopia with or without astigmatism.
Participants were randomized to receive WF-guided or WF-optimized LASIK with the WaveLight Allegretto Eye-Q 400-Hz excimer laser platform (Alcon, Inc., Hüenberg, Switzerland). LASIK flaps were created using the 150-kHz IntraLase iFS (Abbott Medical Optics, Santa Ana, CA). Evaluations included measurement of uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), <5% and <25% contrast sensitivity, and WF aberrometry. Patients also completed a validated questionnaire detailing symptoms on a quantitative scale.
Safety, efficacy, predictability, refractive error, UDVA, CDVA, contrast sensitivity, and higher-order aberrations (HOAs).
The frequency with which the WF-guided and WF-optimized groups achieved postoperative UDVA of ≥ 20/16 or ≥ 20/20 and the frequency with which the groups lost 1 or 2 or more lines or maintained their preoperative CDVA were not statistically different from each other (all P > 0.05). The frequency with which the WF-guided group attained a refractive error within ± 0.25 diopters of emmetropia was higher than in the WF-optimized group (67.6%, 95% confidence interval [CI], 50.4-84.8 vs. 41.2%, 95% CI, 23.2-59.2; P = 0.03). The WF-guided group's mean UDVA was better than the WF-optimized group's UDVA by approximately 1 Early Treatment Diabetic Retinopathy Study line (-0.17 ± 0.11 logarithm of the minimum angle of resolution [logMAR], slightly <20/12 Snellen vs. -0.13 ± 0.12, slightly >20/16; P = 0.05). There were no statistically significant differences in contrast sensitivity, astigmatism, coma, or higher-order root mean square error between the groups (all P > 0.05), but the WF-guided group had less trefoil compared with the WF-optimized group (0.14 ± 0.07 vs. 0.20 ± 0.09; P < 0.01). There were no statistically significant differences in subjective parameters between the groups (all P > 0.05).
Wavefront-guided and WF-optimized LASIK using the Alcon WaveLight Allegretto Eye-Q 400-Hz excimer laser platform provide similar results in myopic patients; however, the WF-guided approach may yield small gains in visual acuity, predictability, and HOAs.
Details
- Title: Subtitle
- One-year outcomes from a prospective, randomized, eye-to-eye comparison of wavefront-guided and wavefront-optimized LASIK in myopes
- Creators
- Christopher S Sáles - Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CaliforniaEdward E Manche - Byers Eye Institute, Stanford University School of Medicine, Palo Alto, California. Electronic address: edward.manche@stanford.edu
- Resource Type
- Journal article
- Publication Details
- Ophthalmology (Rochester, Minn.), Vol.120(12), pp.2396-2402
- DOI
- 10.1016/j.ophtha.2013.05.010
- PMID
- 23778091
- ISSN
- 0161-6420
- eISSN
- 1549-4713
- Language
- English
- Date published
- 12/2013
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984109899502771
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