Journal article
Ontogeny of Eyeblink Conditioned Response Timing in Rats
Behavioral neuroscience, Vol.117(2), pp.283-291
04/2003
DOI: 10.1037/0735-7044.117.2.283
PMID: 12708525
Abstract
Eyeblink conditioned response (CR) timing was assessed in adult and infant rats. In Experiment 1, adult rats were trained with a 150-ms tone conditioned stimulus (CS) paired with a periorbital shock unconditioned stimulus (US; presented at 200- or 500-ms interstimulus intervals [ISIs]). The rats acquired CRs with 2 distinct peaks that occurred just before the US onset times. Experiments 2 and 3 examined developmental changes in CR timing in pups trained on Postnatal Days 24-26 or 32-34. Experiment 3 used a delay conditioning procedure in which the tone CS continued throughout the ISIs. Pups of both ages exhibited robust conditioning. However, there were age-related increases in the percentage of double-peaked CRs and in CR timing precision. Ontogenetic changes in eyeblink CR timing may be related to developmental changes in cerebellar cortical or hippocampal function.
Details
- Title: Subtitle
- Ontogeny of Eyeblink Conditioned Response Timing in Rats
- Creators
- John H Freeman - Department of Psychology, University of IowaDaniel A Nicholson - Department of Psychology, University of IowaAdam S Muckler - Department of Psychology, University of IowaChristine A Rabinak - Department of Psychology, University of IowaNorma T DiPietro - Department of Psychology, University of Iowa
- Resource Type
- Journal article
- Publication Details
- Behavioral neuroscience, Vol.117(2), pp.283-291
- Publisher
- American Psychological Association
- DOI
- 10.1037/0735-7044.117.2.283
- PMID
- 12708525
- ISSN
- 0735-7044
- eISSN
- 1939-0084
- Language
- English
- Date published
- 04/2003
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984065859802771
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