Ontogeny of cardiac rate regulation and brown fat thermogenesis in golden hamsters (Mesocricetus auratus)

M S Blumberg

doi:10.1007/s003600050108

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Ontogeny of cardiac rate regulation and brown fat thermogenesis in golden hamsters (Mesocricetus auratus)

Journal article

Peer reviewed

Ontogeny of cardiac rate regulation and brown fat thermogenesis in golden hamsters (Mesocricetus auratus)

M S Blumberg

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Vol.167(8), pp.552-557

11/1997

DOI: 10.1007/s003600050108

PMID: 9404016

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Abstract

It was shown previously in infant rats (Rattus norvegicus) that the ability to produce heat in the cold using brown adipose tissue (BAT) is closely related to the ability to maintain cardiac rate. When the limits of BAT thermogenesis were exceeded, interscapular temperature (which reflects the temperature of the interscapular BAT depot) and cardiac rate fell together. As an extension of this earlier study, the relation between BAT thermogenesis and cardiac rate was examined here in the golden hamster (Mesocricetus auratus), a species whose young do not exhibit BAT thermogenesis until the end of the 2nd week postpartum. It was found that 3 to 12-day-old hamsters were unable to increase shivering or nonshivering thermogenesis in the cold and exhibited decreases in cardiac rate that proceeded in lock-step with decreases in interscapular temperature. In contrast, as the thermogenic capability of hamsters increased after 12 days of age, cardiac rate was maintained within narrow limits across a wide range of air temperatures. These results support the hypothesis that heat produced by BAT helps to warm the heart and thus aids in the maintenance of cardiac rate during cold exposure.

Animals, Newborn

Heart Rate

Cricetinae

Heart - growth & development

Body Temperature Regulation

Oxygen Consumption

Adipose Tissue, Brown - physiology

Homeostasis

Rats

Male

Regression Analysis

Animals

Aging - physiology

Adipose Tissue, Brown - growth & development

Female

Mesocricetus - physiology

Details

Title: Subtitle: Ontogeny of cardiac rate regulation and brown fat thermogenesis in golden hamsters (Mesocricetus auratus)
Creators: M S Blumberg - Department of Psychology, University of Iowa, Iowa City 52242, USA. mark-blumberg@uiowa.edu
Resource Type: Journal article
Publication Details: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, Vol.167(8), pp.552-557
DOI: 10.1007/s003600050108
PMID: 9404016
NLM abbreviation: J Comp Physiol B
ISSN: 0174-1578
eISSN: 1432-136X
Publisher: Germany
Grant note: MH50701 / NIMH NIH HHS
Language: English
Date published: 11/1997
Academic Unit: Psychological and Brain Sciences; Iowa Neuroscience Institute; Biology
Record Identifier: 9984002301202771

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