Journal article
Open-chest epicardial "surgical" defibrillation: biphasic versus monophasic waveform shocks
Pacing and clinical electrophysiology, Vol.26(3), pp.711-718
03/2003
DOI: 10.1046/j.1460-9592.2003.00121.x
PMID: 12698671
Abstract
The aim of the study was to compare biphasic versus monophasic shocks for open-chest epicardial defibrillation. Transthoracic biphasic waveform shocks require less energy to terminate ventricular fibrillation compared to monophasic waveform shocks. However, if biphasic shocks are effective for open-chest epicardial ("surgical") defibrillation has not been established. Twenty-eight anesthetized adult swine (15-25 kg) underwent a midline sternotomy. Ventricular fibrillation was electrically induced. After 15 seconds of ventricular fibrillation, each pig in group 1 (n = 16) randomly received damped sinusoidal monophasic epicardial shocks and truncated exponential biphasic epicardial shocks from large (44.2 cm2) paddle electrodes at eight energy levels (2-50 J). Pigs in group 2 (n = 12) received monophasic and truncated exponential biphasic shocks from small (15.9 cm2) paddle electrodes. In group 1 (large paddle electrodes), the overall percent shock success rose from 15 +/- 9% at 2 J to 97 +/- 3% at 50 J. In this group there was no significant difference in percent of shock success between damped sinusoidal monophasic and biphasic waveform shocks. In group 2 (small paddle electrodes), biphasic shocks yielded a significantly higher percent of shock success than monophasic shocks at mid-energy levels from 7 to 20 J (all P < 0.01). With small surgical paddle electrodes, biphasic waveform shocks demonstrated a significantly higher percent of shock success rate compared to monophasic waveform shocks. With large paddle electrodes, the two waveforms were equally effective.
Details
- Title: Subtitle
- Open-chest epicardial "surgical" defibrillation: biphasic versus monophasic waveform shocks
- Creators
- Yi Zhang - Cardiovascular Center, College of Medicine, University of Iowa, Iowa City, Iowa, USALoyd R DaviesWilliam J CoddingtonM Bridget ZimmermanScott WuthrichJanice L JonesRichard E Kerber
- Resource Type
- Journal article
- Publication Details
- Pacing and clinical electrophysiology, Vol.26(3), pp.711-718
- Publisher
- United States
- DOI
- 10.1046/j.1460-9592.2003.00121.x
- PMID
- 12698671
- ISSN
- 0147-8389
- eISSN
- 1540-8159
- Grant note
- HL53284-05 / NHLBI NIH HHS HL24606 / NHLBI NIH HHS
- Language
- English
- Date published
- 03/2003
- Academic Unit
- Biostatistics
- Record Identifier
- 9983997351902771
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