Journal article
Operative Time and Risk of Surgical Site Infection and Periprosthetic Joint Infection: A Systematic Review and Meta-Analysis
The Iowa orthopaedic journal, Vol.42(1), pp.155-161
06/01/2022
PMCID: PMC9210401
PMID: 35821941
Appears in Diamond Open Access
Abstract
BackgroundThe purpose of this study was to perform a systematic review and meta-analysis on the association between operative time and peri-prosthetic joint infection (PJI) after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA). MethodsPubMed, Embase, and Cochrane CENTRAL databases were searched for relevant articles dating 2000-2020. Relationship of operative time and PJI rate in primary total joint arthroplasty (TJA) was evaluated by pooled odds ratios (OR) and 95% confidence intervals. ResultsSix studies were identified for meta-analysis. TJA lasting greater than 120 minutes had greater odds of PJI (OR, 1.63 [1.00-2.66], p=0.048). Similarly, there were greater odds of PJI for TJA procedures lasting greater than 90 minutes (OR, 1.65 [1.27-2.14]; p<0.001). Separate analyses of TKA (OR, 2.01 [0.76-5.30]) and THA (OR, 1.06 [0.80-1.39]) demonstrated no difference in rates of PJI in cases of operative time ≥ 120 minutes versus cases < 120 minutes (p>0.05 for all). Using any surgical site infection (SSI) as an endpoint, both TJA (OR, 1.47 [1.181.83], p<0.001) and TKA (OR, 1.50 [1.08-2.08]; p=0.016) procedures lasting more versus less than 120 minutes demonstrated significantly higher odds of SSI. ConclusionFollowing TJA, rates of SSI and PJI are significantly greater in procedures ≥120 minutes in duration relative to those < 120 minutes. When analyzing TKA separately, higher rates of SSI were observed in procedures ≥ 120 minutes in duration relative to those <120 minutes. Rates of PJI in TKA or THA procedures alone were not significantly impacted by operative time. Level of Evidence: V.
Details
- Title: Subtitle
- Operative Time and Risk of Surgical Site Infection and Periprosthetic Joint Infection: A Systematic Review and Meta-Analysis
- Creators
- Noah M SciglianoChristopher N CarenderNatalie A GlassJennifer DebergNicholas A Bedard
- Resource Type
- Journal article
- Publication Details
- The Iowa orthopaedic journal, Vol.42(1), pp.155-161
- Publisher
- Dept. of Orthopaedics, The University of Iowa; United States
- PMID
- 35821941
- PMCID
- PMC9210401
- ISSN
- 1541-5457
- eISSN
- 1555-1377
- Language
- English
- Date published
- 06/01/2022
- Academic Unit
- Orthopedics and Rehabilitation; Nursing; Hardin Library
- Record Identifier
- 9984296999202771
Metrics
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