Operative time and other outcomes of the electrothermal bipolar vessel sealing system (LigaSure) versus other methods for surgical hemostasis: a meta-analysis

Alex Macario; Franklin Dexter; Jennifer Sypal; Ned Cosgriff; B Todd Heniford

doi:10.1177/1553350608324933

Back

Operative time and other outcomes of the electrothermal bipolar vessel sealing system (LigaSure) versus other methods for surgical hemostasis: a meta-analysis

Journal article

Peer reviewed

Operative time and other outcomes of the electrothermal bipolar vessel sealing system (LigaSure) versus other methods for surgical hemostasis: a meta-analysis

Alex Macario, Franklin Dexter, Jennifer Sypal, Ned Cosgriff and B Todd Heniford

Surgical innovation, Vol.15(4), pp.284-291

12/2008

DOI: 10.1177/1553350608324933

PMID: 18945705

View Online

Abstract

A meta-analysis was performed of 29 prospective, randomized trials (published January 1, 2000, to August 14, 2007) comparing an electrothermal bipolar vessel sealing system (EBVS-LigaSure, Covidien) (total n = 1107 patients) with either clamping with suture ligation/ electrocauterization (n = 1079 patients) or ultrasonic energy (eg, Harmonic Scalpel, Johnson & Johnson). Hemorrhoidectomy (12 articles), hysterectomy (4 articles), and thyroidectomy (3 articles) were the most common procedures. For 15 of 26 studies reporting standard deviations, the normalized mean operative time reduction for EBVS equaled 28% (95% confidence interval [CI] 18%-39%, P < .0001) compared with conventional surgical hemostasis. Operative time was reduced with EBVS in 24 of 26 studies (P < .0001). EBVS was associated with 43 mL (95% CI 14-73 mL, P = .0021) less blood loss, fewer complications (odds ratio 0.66, 95% CI 0.47-0.92, P = .02), and mean reduction in postoperative pain of 2.8 units (95% CI 1.5-4.1, P < .0001). Five studies used ultrasonic energy as the comparator, but none reported standard deviation so data could not be pooled.

Length of Stay

Pain, Postoperative - prevention & control

Blood Loss, Surgical - prevention & control

Electrocoagulation - adverse effects

Time Factors

Humans

Electrocoagulation - instrumentation

Treatment Outcome

Hemostasis, Surgical - instrumentation

Hemostasis, Surgical - adverse effects

Details

Title: Subtitle: Operative time and other outcomes of the electrothermal bipolar vessel sealing system (LigaSure) versus other methods for surgical hemostasis: a meta-analysis
Creators: Alex Macario - Department of Anesthesia, Stanford University School of Medicine, California 94305-5640, USA. Amaca@stanford.edu
Franklin Dexter
Jennifer Sypal
Ned Cosgriff
B Todd Heniford
Resource Type: Journal article
Publication Details: Surgical innovation, Vol.15(4), pp.284-291
Publisher: United States
DOI: 10.1177/1553350608324933
PMID: 18945705
ISSN: 1553-3506
eISSN: 1553-3514
Language: English
Date published: 12/2008
Academic Unit: Health Management and Policy; Anesthesia
Record Identifier: 9983806268102771

Metrics

24 Record Views

73 Times Cited - Web of Science