Ophthalmic manifestations of allergic fungal sinusitis

K D Carter; S M Graham; K M Carpenter

doi:10.1016/S0002-9394(98)00371-7

Back

Ophthalmic manifestations of allergic fungal sinusitis

Journal article

Peer reviewed

Ophthalmic manifestations of allergic fungal sinusitis

K D Carter, S M Graham and K M Carpenter

American journal of ophthalmology, Vol.127(2), pp.189-195

02/1999

DOI: 10.1016/S0002-9394(98)00371-7

PMID: 10030562

View Online

Abstract

To highlight allergic fungal sinusitis as a cause of ophthalmic and sinus problems by identifying the profile of the patient with allergic fungal sinusitis and presenting a successful treatment approach. Six consecutive cases of patients with ophthalmic manifestations of allergic fungal sinusitis were reviewed. Ophthalmic findings, sinus involvement, mycology, immune response, imaging studies, and treatment were examined. The characteristics of this patient group with ophthalmic manifestations of allergic fungal sinusitis were compared with those of the general group of patients with allergic fungal sinusitis. All six patients had proptosis. One had symptomatic diplopia and one had visual loss. Imaging studies, fungal characterization, and immune profiles were similar to the reported allergic fungal sinusitis population. After treatment there was no recurrence of ophthalmic or sinus symptoms at a mean follow-up of 34 months (range, 8 to 48 months). There were no complications of treatment. Initial diagnosis of allergic fungal sinusitis requires suspicion on the part of the ophthalmologist. Proptosis is the most common ophthalmic sign. Differentiation from invasive forms of fungal sinus disease is crucial, because systemic antifungal medication and extensive surgical tissue debridement are not required in allergic fungal sinusitis. Treatment consists of extirpation of the allergic mucin and fungus, sinus aeration, and systemic and topical corticosteroids.

Glucocorticoids - therapeutic use

Humans

Fungi - isolation & purification

Mycoses - microbiology

Male

Tomography, X-Ray Computed

Antifungal Agents - therapeutic use

Eye Infections, Fungal - diagnostic imaging

Sinusitis - microbiology

Adult

Female

Mycoses - diagnostic imaging

Exophthalmos - microbiology

Drug Therapy, Combination

Hypersensitivity, Immediate - diagnosis

Hypersensitivity, Immediate - microbiology

Hypersensitivity, Immediate - drug therapy

Paranasal Sinuses - diagnostic imaging

Paranasal Sinuses - microbiology

Exophthalmos - diagnostic imaging

Exophthalmos - drug therapy

Eye Infections, Fungal - etiology

Immunoglobulin E - analysis

Eye Infections, Fungal - drug therapy

Adolescent

Mycoses - drug therapy

Aged

Sinusitis - diagnostic imaging

Sinusitis - drug therapy

Therapeutic Irrigation

Details

Title: Subtitle: Ophthalmic manifestations of allergic fungal sinusitis
Creators: K D Carter - Department of Ophthalmology and Visual Sciences, University of Iowa College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA
S M Graham
K M Carpenter
Resource Type: Journal article
Publication Details: American journal of ophthalmology, Vol.127(2), pp.189-195
Publisher: United States
DOI: 10.1016/S0002-9394(98)00371-7
PMID: 10030562
ISSN: 0002-9394
eISSN: 1879-1891
Language: English
Date published: 02/1999
Academic Unit: Neurosurgery; Otolaryngology; Ophthalmology and Visual Sciences
Record Identifier: 9983980395002771

Metrics

22 Record Views

36 Times Cited - Web of Science