Journal article
Opsonin-independent phagocytosis by human alveolar macrophages: augmentation by human plasma fibronectin
The American review of respiratory disease, Vol.125(5), pp.607-609
05/1982
DOI: 10.1164/arrd.1982.125.5.607
PMID: 7081821
Abstract
A trypsin-sensitive membrane recognition unit that mediates phagocytosis of particulate activators of the human alternative complement pathway is present on human alveolar macrophages. Fragmented human plasma fibronectin selected by affinity chromatography with a monoclonal antifibronectin antibody augments this capacity. These data suggest a nonimmune mechanism for the clearance of some microorganisms from the opsonin-deficient microenvironment of the lung in which the alveolar macrophage is the principal resident phagocyte.
Details
- Title: Subtitle
- Opsonin-independent phagocytosis by human alveolar macrophages: augmentation by human plasma fibronectin
- Creators
- J K CzopS E McGowanD M Center
- Resource Type
- Journal article
- Publication Details
- The American review of respiratory disease, Vol.125(5), pp.607-609
- Publisher
- United States
- DOI
- 10.1164/arrd.1982.125.5.607
- PMID
- 7081821
- ISSN
- 0003-0805
- eISSN
- 2376-3752
- Grant note
- N0. RR-05669 / NCRR NIH HHS AI-17132 / NIAID NIH HHS AI-07722 / NIAID NIH HHS
- Language
- English
- Date published
- 05/1982
- Academic Unit
- International Programs; Internal Medicine
- Record Identifier
- 9983984522802771
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