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Optical Coherence Angiographic Demonstration of Retinal Changes From Chronic Optic Neuropathies
Journal article   Open access   Peer reviewed

Optical Coherence Angiographic Demonstration of Retinal Changes From Chronic Optic Neuropathies

John J Chen, Jackson E AbouChehade, Raymond Iezzi, Jacqueline A Leavitt and Randy H Kardon
Neuro-Ophthalmology, Vol.41(2), pp.76-83
03/04/2017
DOI: 10.1080/01658107.2016.1275703
PMCID: PMC5354095
PMID: 28348629
url
https://doi.org/10.1080/01658107.2016.1275703View
Published (Version of record) Open Access

Abstract

Glaucoma causes a decrease in peripapillary perfused capillary density on optical coherence tomography (OCT) angiography. However, other chronic optic neuropathies have not been explored with OCT angiography to see if these changes were specific to glaucoma. The authors evaluated OCT angiography in 10 patients who suffered various kinds of chronic optic neuropathies, including optic neuritis and ischaemic optic neuropathy, and found that all optic neuropathies showed a decrease in peripapillary vessel density on OCT angiography, regardless of the aetiology of the optic neuropathy. The peripapillary vessel loss on OCT angiography correlated well with the areas of retinal nerve fibre layer thinning seen on OCT.
optic neuropathy OCT angiography peripapillary capillaries

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