Optical trapping force reduction and manipulation of nanoporous beads

Tao Wang; Fan Jiang; Stefan Oehrlein; Erliang Zeng; Ryan Kershner; Franco Cerrina

doi:10.1063/1.3703604

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Optical trapping force reduction and manipulation of nanoporous beads

Journal article

Open access

Peer reviewed

Optical trapping force reduction and manipulation of nanoporous beads

Tao Wang, Fan Jiang, Stefan Oehrlein, Erliang Zeng, Ryan Kershner and Franco Cerrina

Applied physics letters, Vol.100(15), pp.153702-153702-3

04/11/2012

DOI: 10.1063/1.3703604

PMCID: PMC3338583

PMID: 22550360

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Abstract

We studied the interaction of infrared optical traps with controlled-pore glass (CPG) beads in aqueous medium. The lateral optical trapping force and stiffness were experimentally found considerably smaller than those of their solid counterparts. The simulation using an average refractive index revealed significant losses of effective trapping efficiency, which quantitatively agreed well with experimentally fitted curves. This effect was ascribed to the reduced relative refractive index of medium-filled CPG beads with respect to the medium. Combining optical trapping with mechanical confinements, we demonstrated a microfluidic platform allowing for the synthesis of multiple DNA oligonucleotide sequences on individual beads of interest.

Details

Title: Subtitle: Optical trapping force reduction and manipulation of nanoporous beads
Creators: Tao Wang - Department of Electrical Engineering, Center for Nano Science and Technology, University of Notre Dame, Notre Dame, Indiana 46556, USA
Fan Jiang - Department of Electrical Engineering, Center for Nano Science and Technology, University of Notre Dame, Notre Dame, Indiana 46556, USA
Stefan Oehrlein - Department of Electrical Engineering, Center for Nano Science and Technology, University of Notre Dame, Notre Dame, Indiana 46556, USA
Erliang Zeng - Department of Electrical Engineering, Center for Nano Science and Technology, University of Notre Dame, Notre Dame, Indiana 46556, USA
Ryan Kershner - Department of Electrical Engineering, Center for Nano Science and Technology, University of Notre Dame, Notre Dame, Indiana 46556, USA
Franco Cerrina - Department of Electrical Engineering, Center for Nano Science and Technology, University of Notre Dame, Notre Dame, Indiana 46556, USA
Resource Type: Journal article
Publication Details: Applied physics letters, Vol.100(15), pp.153702-153702-3
Publisher: American Institute of Physics
DOI: 10.1063/1.3703604
PMID: 22550360
PMCID: PMC3338583
ISSN: 0003-6951
eISSN: 1077-3118
Language: English
Date published: 04/11/2012
Academic Unit: Preventive and Community Dentistry; Roy J. Carver Department of Biomedical Engineering; Iowa Neuroscience Institute; Biostatistics; Dental Research
Record Identifier: 9984065469902771

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