Journal article
Optimizing the imaging of the monkey auditory cortex: sparse vs. continuous fMRI
Magnetic resonance imaging, Vol.27(8), pp.1065-1073
10/01/2009
DOI: 10.1016/j.mri.2009.01.018
PMID: 19269764
Abstract
The noninvasive imaging of the monkey auditory system with functional magnetic resonance imaging (fMRI) can bridge the gap between electrophysiological Studies in monkeys and imaging studies in humans. Some of the recent imaging of monkey auditory cortical and subcortical structures relies on a technique of "sparse imaging," which was developed in human Studies to sidestep the negative influence of scanner noise by adding periods of silence in between volume acquisition. Among the various aspects that have gone into the ongoing optimization of fMRI of the monkey auditory cortex, replacing the more common continuous-imaging paradigm with sparse irnaging seemed to LIS to make the most obvious difference in the amount of activity that we could reliably obtain from awake or anesthetized animals. Here. we directly compare the sparse- and continuous-imaging paradigms in anesthetized animals. We document a strikingly greater auditory response with sparse irnaging, both quantitatively and qualitatively, which includes a more expansive and robust tonotopic organization. There were instances where continuous imaging Could better reveal organizational properties that sparse irnaging missed, Such as aspects of the hierarchical organization of auditory cortex. We consider the choice of imaging paradigm its a key component in optimizing the fMRI of the monkey auditory cortex. (C) 2009 Elsevier Inc. All rights reserved.
Details
- Title: Subtitle
- Optimizing the imaging of the monkey auditory cortex: sparse vs. continuous fMRI
- Creators
- Christopher I. Petkov - University of Newcastle AustraliaChristoph Kayser - Max Planck Institute for Biological CyberneticsMark Augath - Max Planck Institute for Biological CyberneticsNikos K. Logothetis - University of Manchester
- Resource Type
- Journal article
- Publication Details
- Magnetic resonance imaging, Vol.27(8), pp.1065-1073
- Publisher
- Elsevier
- DOI
- 10.1016/j.mri.2009.01.018
- PMID
- 19269764
- ISSN
- 0730-725X
- eISSN
- 1873-5894
- Number of pages
- 9
- Language
- English
- Date published
- 10/01/2009
- Academic Unit
- Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
- Record Identifier
- 9984360134302771
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