Journal article
Oral Antivirals for the Acute Treatment of Recurrent Herpes Labialis
The Annals of pharmacotherapy, Vol.38(4), pp.705-709
04/2004
DOI: 10.1345/aph.1D285
PMID: 14966254
Abstract
OBJECTIVE
To evaluate the use and benefit of oral antivirals in the acute treatment of episodic, recurrent herpes labialis.
DATA SOURCES
A literature search was performed in MEDLINE (1966—August 2003) using acyclovir, famciclovir, valacyclovir, cold sores, herpes labialis, and HSV-1 as search terms.
DATA SYNTHESIS
We reviewed 5 placebo-controlled and 2 comparative studies evaluating oral antivirals for acute treatment of recurrent herpes labialis. No studies directly compared different antivirals. Studies discussing the efficacy of antivirals for chronic suppression of herpes simplex virus-1 infection were not included.
CONCLUSIONS
Treatment with oral antivirals decreases the duration of lesion episodes and pain by approximately one day; however, the antivirals do not abort lesions from developing. Clinical implications of these results appear relatively modest.
Details
- Title: Subtitle
- Oral Antivirals for the Acute Treatment of Recurrent Herpes Labialis
- Creators
- Lori A Jensen - University of IowaJames D Hoehns - James D Hoehns PharmD BCPS, Assistant Professor (Clinical), College of Pharmacy, University of Iowa; Clinical Pharmacist, Northeast Iowa Family Practice Center, Waterloo, IACindy L Squires - Cindy L Squires MD PhD, at time of writing, Resident Physician, Northeast Iowa Family Practice Center; now, Staff Physician, Affiliates of Family Practice, Cedar Rapids, IA
- Resource Type
- Journal article
- Publication Details
- The Annals of pharmacotherapy, Vol.38(4), pp.705-709
- DOI
- 10.1345/aph.1D285
- PMID
- 14966254
- ISSN
- 1060-0280
- eISSN
- 1542-6270
- Language
- English
- Date published
- 04/2004
- Academic Unit
- Pharmacy Practice and Science
- Record Identifier
- 9984366029002771
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