Journal article
Oral ulcer activity in Behcet's disease: Poor medication adherence is an underestimated risk factor
European journal of rheumatology, Vol.4(2), pp.109-112
06/01/2017
DOI: 10.5152/eurjrheum.2017.160094
PMCID: PMC5473444
PMID: 28638682
Abstract
Objective: The aim of this study was to evaluate the relationship between oral ulcer activity and medication adherence according to gender in Behcet's disease (BD) patients.
Material and Methods: The study group included 330 BD patients (F/M: 167/163, mean age: 38.5 +/- 10.5 years). Oral ulcer activity and medication adherence were evaluated in the previous month. Medication adherence was evaluated using the 8-item Morisky Medication Adherence Scale (MMAS-8) having a score range of "0" to "8" with high scores indicating better adherence. Low adherence was defined as < 6 points on MMAS-8.
Results: Over half of the group had active oral ulcers (n= 219, 66.4%) within the month preceding the visit. The number of oral ulcers was significantly higher in female patients with low medication adherence (2.39 +/- 3.24) than in the rest of the female group (1.28 +/- 2.05; p= 0.023). Although a similar trend was also observed in male patients (2.14 +/- 3.3 vs. 1.81 +/- 2.31), a significant relationship was not observed (p= 0.89). The frequency of medication intake per day was lower in patients with high medication adherence than in the rest of the study group (p= 0.04).
Conclusion: Low medication adherence is a hidden risk factor in the management of BD. Poor adherence was associated with oral ulcer activity in female BD patients.
Details
- Title: Subtitle
- Oral ulcer activity in Behcet's disease: Poor medication adherence is an underestimated risk factor
- Creators
- Gonca Mumcu - Marmara UniversityFatma Alibaz-Oner - Marmara UniversitySibel Yilmaz Oner - Marmara UniversityGulsen Ozen - Marmara UniversityPamir Atagunduz - Marmara UniversityNevsun Inanc - Marmara UniversityLeyla Koksal - Marmara UniversityTulin Ergun - Marmara UniversityHaner Direskeneli - Marmara University
- Resource Type
- Journal article
- Publication Details
- European journal of rheumatology, Vol.4(2), pp.109-112
- DOI
- 10.5152/eurjrheum.2017.160094
- PMID
- 28638682
- PMCID
- PMC5473444
- NLM abbreviation
- Eur J Rheumatol
- ISSN
- 2147-9720
- eISSN
- 2148-4279
- Publisher
- Aves
- Number of pages
- 4
- Language
- English
- Date published
- 06/01/2017
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984702896002771
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