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Orbital implant exposure after Acanthamoeba panophthalmitis
Journal article   Open access   Peer reviewed

Orbital implant exposure after Acanthamoeba panophthalmitis

Meredith S Baker, Amanda C Maltry, Nasreen A Syed and Richard C Allen
American Journal of Ophthalmology Case Reports, Vol.10, pp.48-50
2018
DOI: 10.1016/j.ajoc.2018.01.043
PMCID: PMC5956657
PMID: 29780912
url
https://doi.org/10.1016/j.ajoc.2018.01.043View
Published (Version of record) Open Access

Abstract

Purpose: Acanthamoeba is a protozoa that can lead to severe ocular disease and sequelae. Although intraocular Acanthamoeba infection is rare, the following case demonstrates an unusual presentation of recurrent Acanthamoeba infection in a 30 year old contact lens wearing male.Observations: After presenting with recurrent Acanthamoeba keratitis and undergoing various treatments, the patient developed nodular scleritis, which evolved into panophthalmitis, and ultimately, required enucleation. Eight months post-operatively, the patient developed orbital implant exposure secondary to persistent Acanthamoeba infection and underwent removal of the implant and aggressive, systemic treatment involving a multispecialty care team. He then underwent placement of a dermis fat graft and had no signs of persistent infection at the time of last follow-up, which was 24 months after placement of the dermis fat graft.Conclusions: and Importance: To the authors' knowledge, this is the first known case of Acanthamoeba infection causing orbital implant exposure. Persistent infection should be considered in Acanthamoeba patients who have undergone enucleation and have orbital implant exposure. Better knowledge regarding the pathogenesis and extracorneal complications of this challenging disease may improve patient care and outcomes.

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