Journal article
Organization, barrier function and antimicrobial lipids of the oral mucosa
International journal of cosmetic science, Vol.35(3), pp.220-223
06/2013
DOI: 10.1111/ics.12038
PMCID: PMC3640763
PMID: 23320785
Abstract
As one moves from the skin across the vermilion region of the lip and into the oral cavity, the oral mucosa is encountered. The oral mucosa consists of connective tissue known as the lamina propria covered by a stratified squamous epithelium. In the regions of the hard palate and gingiva, the epithelium is keratinized like the epidermis. In the buccal region, the floor of the mouth and the underside of the tongue, the epithelium is non-keratinized. The epithelium on the dorsum of the tongue is a specialized epithelium, but can be approximated as a mosaic of keratinized and non-keratinized epithelia. The non-keratinized epithelial regions do not produce a stratum corneum. Nuclei with intact DNA are retained in the superficial cells. In all regions, the outer portions of the epithelium provide a protective permeability barrier, which varies regionally. Antimicrobial lipids at the surfaces of the oral mucosa are an integral part of innate immunity.
Details
- Title: Subtitle
- Organization, barrier function and antimicrobial lipids of the oral mucosa
- Creators
- D V Dawson - Dows Institute for Dental Research, University of Iowa, N450 DSB, Iowa City, Iowa 52242, USAD R DrakeJ R HillK A BrogdenC L FischerP W Wertz
- Resource Type
- Journal article
- Publication Details
- International journal of cosmetic science, Vol.35(3), pp.220-223
- Publisher
- England
- DOI
- 10.1111/ics.12038
- PMID
- 23320785
- PMCID
- PMC3640763
- ISSN
- 0142-5463
- eISSN
- 1468-2494
- Grant note
- R01 DE014390 / NIDCR NIH HHS R01 DE018032 / NIDCR NIH HHS
- Language
- English
- Date published
- 06/2013
- Academic Unit
- Oral Pathology, Radiology and Medicine; Endodontics; Biostatistics; Pediatric Dentistry; Dental Research; Periodontics
- Record Identifier
- 9983985845402771
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