Journal article
Outcome in Nonseptic Spontaneous Superior Sagittal Sinus Thrombosis in Adults
Cerebrovascular diseases (Basel, Switzerland), Vol.1(4), pp.231-234
1991
DOI: 10.1159/000108848
Abstract
We reviewed clinical features and outcomes of 16 patients (3 men and 13 women) aged 18–68 years, with nonseptic, nontraumatic superior sagittal sinus thrombosis (SSST). Most common risk factors were oral contraceptives, a postpartum state or malignancy. Two patients were noted to have a ‘lupus anticoagulant’; 1 of these had prior venous thrombosis in the legs and recurrent spontaneous abortions but no antiphospholipid antibodies. Five patients had ;poor outcomes, including 4 deaths. Of the 11 patients with good outcomes, 9 had no residual deficits. Intracranial hemorrhage was noted on initial CT in 3 patients. One had hemorrhagic transformation of a bland cerebral infarction without use of anticoagulants, as did 1 after receiving only 1,600 IU of intravenous heparin. Of the 11 patients who had a good outcome, 5 received full-dose intravenous heparin. Of the 5 patients who had a poor outcome, none received full-dose heparin due to the presence of either a large infarction or hemorrhage. Due to its infrequent occurrence and heterogenous nature, recommendations regarding heparin therapy for patients with nonseptic SSST should be individualized.
Details
- Title: Subtitle
- Outcome in Nonseptic Spontaneous Superior Sagittal Sinus Thrombosis in Adults
- Creators
- Jeffrey M KaplanJosé BillerHarold P Adams Jr
- Resource Type
- Journal article
- Publication Details
- Cerebrovascular diseases (Basel, Switzerland), Vol.1(4), pp.231-234
- Publisher
- Basel, Switzerland
- DOI
- 10.1159/000108848
- ISSN
- 1015-9770
- eISSN
- 1421-9786
- Number of pages
- 4
- Language
- English
- Date published
- 1991
- Academic Unit
- Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984020714602771
Metrics
10 Record Views