Journal article
Outcomes Vary Significantly Using a Tiered Approach to Define Success After Total Knee Arthroplasty
The Journal of arthroplasty, Vol.37(7), pp.1266-1272
07/2022
DOI: 10.1016/j.arth.2022.02.065
PMID: 35202758
Abstract
Patient-reported outcome measures (PROM) allow assessment of clinical outcomes following primary total knee arthroplasty (TKA). The purpose of this study is to use progressively more stringent definitions of success to examine clinical outcomes of primary TKA at 1 year postoperatively and to determine which demographic variables were associated with achieving clinical success.
The American Joint Replacement Registry was queried from 2012 to 2020 for primary TKA. Patients who completed the following PROMs preoperatively and 1 year postoperatively were included: Western Ontario and McMaster Universities Arthritis Index (WOMAC), Knee Injury and Osteoarthritis Outcome Score (KOOS), and KOOS for Joint Replacement (KOOS JR). Mean PROM scores were determined for each visit and between-visit changes were evaluated using paired t-tests. Rates of achievement of minimal clinically important difference (MCID) by distribution-based and anchor-based criteria, Patient Acceptable Symptom State, and substantial clinical benefit were calculated. Logistic regression was used to evaluate the association between demographic variables and odds of clinical success.
In total, 12,341 TKAs were included. Mean improvement in PROM scores were as follows: KOOS JR, 29; WOMAC-Pain, 33; and WOMAC-Function, 31 (P < .0001 for all). Rates of achievement of each metric were the following: distribution-based MCID, 84%-87%; anchor-based MCID, 46%-79%; Patient Acceptable Symptom State, 54%-82%; and substantial clinical benefit, 68%-81%. Patient age and gender were the most influential demographic factors on achievement of clinical success.
Clinical outcomes at 1 year following TKA vary significantly when using a tiered approach to define success. A tiered approach to interpretation of PROMs should be considered for future research and clinical assessment.
Details
- Title: Subtitle
- Outcomes Vary Significantly Using a Tiered Approach to Define Success After Total Knee Arthroplasty
- Creators
- Christopher N. Carender - University of IowaNatalie A. Glass - University of IowaAyushmita De - American Academy of Orthopaedic SurgeonsKevin J. Bozic - The University of Texas at AustinJohn J. Callaghan - University of IowaNicholas A. Bedard - Mayo Clinic
- Resource Type
- Journal article
- Publication Details
- The Journal of arthroplasty, Vol.37(7), pp.1266-1272
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.arth.2022.02.065
- PMID
- 35202758
- ISSN
- 0883-5403
- eISSN
- 1532-8406
- Language
- English
- Date published
- 07/2022
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Orthopedics and Rehabilitation
- Record Identifier
- 9984548856802771
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