Journal article
Outcomes and Complications in Management of Congenital Myopathy Early-Onset Scoliosis
Journal of pediatric orthopaedics, Vol.41(9), pp.531-536
10/01/2021
DOI: 10.1097/BPO.0000000000001922
PMID: 34325442
Abstract
Congenital myopathies (CMs) are complex conditions often associated with early-onset scoliosis (EOS). The purpose of this study was to investigate radiographic outcomes in CM patients undergoing EOS instrumentation as well as complications. Secondarily, we sought to compare these patients to a population with higher prevalence, cerebral palsy (CP) EOS patients.
This is a retrospective study of a prospectively collected multicenter registry. The registry was queried for EOS patients with growth-sparing instrumentation (vertical expandable prosthetic titanium ribs, magnetically controlled growing rods, traditional growing rod, or Shilla) and a CM or CP diagnosis with minimum 2 years follow-up. Outcomes included major curve magnitude, T1-S1 height, kyphosis, and complications.
Sixteen patients with CM were included. Six (37.5%) children with CM experienced 11 complications by 2 years. Mean major curve magnitude for CM patients was improved postoperatively and maintained at 2 years (P<0.01), with no significant increase in T1-S1 height or maximum kyphosis(P>0.05). Ninety-seven patients with CP EOS were included as a comparative cohort. Fewer CP patients required baseline respiratory support compared with CM patients (20.0% vs. 92.9%, P<0.01). Fifty-four (55.7%) CP patients experienced a total of 105 complications at 2 years. There was no evidence that the risk of complication or radiographic outcomes differs between cohorts at 2 years, though CP EOS patients experienced significant improvement in all measurements at 2 years.
EOS CM children face a high risk of complication after growing instrumentation, with similar curve correction and risk of complication to CP patients.
Level III.
Details
- Title: Subtitle
- Outcomes and Complications in Management of Congenital Myopathy Early-Onset Scoliosis
- Creators
- Lacey Magee - Children's Hospital of PhiladelphiaJoshua T Bram - Children's Hospital of PhiladelphiaJason B Anari - Children's Hospital of PhiladelphiaBrandon Ramo - Texas Scottish Rite Hospital for ChildrenOscar H Mayer - Children's Hospital of PhiladelphiaHiroko Matsumoto - Columbia University Medical CenterJaysson T Brooks - Children's of Mississippi, Jackson, MS.Lindsay Andras - Children's Hospital of Los AngelesRobert Lark - Duke UniversityRyan Fitzgerald - Riley Hospital for ChildrenWalter Truong - Gillette Children's Specialty HealthcareYing Li - C. S. Mott Children's HospitalLawrence Karlin - Boston Children's HospitalRichard Schwend - children's Mercy Hospital, kansas city, MOStuart Weinstein - University of IowaDavid Roye - Columbia University Medical CenterBrian Snyder - Boston Children's HospitalJohn M Flynn - Children's Hospital of PhiladelphiaMatthew Oetgen - Children’s National Health SystemJohn Smith - Primary Children's HospitalPatrick J Cahill - Children's Hospital of PhiladelphiaPediatric Spine Study Group (PSSG)
- Resource Type
- Journal article
- Publication Details
- Journal of pediatric orthopaedics, Vol.41(9), pp.531-536
- DOI
- 10.1097/BPO.0000000000001922
- PMID
- 34325442
- ISSN
- 0271-6798
- eISSN
- 1539-2570
- Language
- English
- Date published
- 10/01/2021
- Academic Unit
- Stead Family Department of Pediatrics; Orthopedics and Rehabilitation
- Record Identifier
- 9984304701002771
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