Journal article
Outcomes of ACL Reconstruction in Patients with Diabetes
Medicine and science in sports and exercise, Vol.48(6), pp.969-973
06/2016
DOI: 10.1249/MSS.0000000000000876
PMCID: PMC4868651
PMID: 26765634
Abstract
Purpose: Diabetes has been associated with adverse outcomes after various types of surgery. There are no previously published data regarding the effect of diabetes on outcomes from anterior cruciate ligament reconstruction (ACLR). The purpose of this study was to test the hypotheses that diabetes is associated with worse clinical outcomes and a higher prevalence of subsequent surgeries after ACLR.
Methods: Anterior cruciate ligament-deficient patients (n = 2198) undergoing unilateral ACLR from a multicenter prospective study were included. Patients who self-reported diabetes on the basis of comorbidity questions before surgery were identified from the database. They were compared with the remainder of the cohort who did not self-report diabetes. All patients were followed up for a minimum of 2 yr after their index surgery. A minimum 2-yr follow-up was attained on 1905/2198 (87%) via completed outcome questionnaires and 2096/2198 (95%) regarding subsequent surgery. The primary outcome measures were three validated outcome instruments. The secondary outcome measure was the incidence of additional surgery on the ipsilateral and contralateral knees.
Results: Patients with diabetes had a significantly higher activity level at 2 yr (OR = 2.96; 95% CI, 1.30-6.77; P = 0.01), but otherwise slightly worse clinical outcomes, compared with patients without diabetes (OR range = 0.42-0.59). The prevalence of subsequent surgeries in patients with diabetes was not significantly different from the prevalence in patients without diabetes.
Conclusions: Patients with diabetes maintain a higher activity level after ACLR despite slightly lower patient-reported outcome scores compared with patients without diabetes and do not have a higher rate of subsequent surgery.
Details
- Title: Subtitle
- Outcomes of ACL Reconstruction in Patients with Diabetes
- Creators
- Robert H Brophy - Department of Orthopaedics, Washington University in St. Louis, Chesterfield, MOLaura J Huston - Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TNRick W Wright - Department of Orthopaedics, Washington University in St. Louis, St. Louis, MOSamuel K Nwosu - Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TNChristopher C Kaeding - Department of Orthopaedics, The Ohio State University, Columbus, OHRichard D Parker - Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OHJack T Andrish - Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OHRobert G Marx - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NYEric C McCarty - Department of Orthopaedics, University of Colorado Denver, Denver, COAnnunziato Amendola - Department of Orthopaedic Surgery, Duke University, Durham, NCBrian R Wolf - Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IAWarren R Dunn - Department of Orthopaedics and Rehabilitation, University of Wisconsin School of Medicine and Public Health, Madison, WIMichelle L Wolcott - Department of Orthopaedics, University of Colorado Denver, Denver, COKurt P Spindler - Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH
- Resource Type
- Journal article
- Publication Details
- Medicine and science in sports and exercise, Vol.48(6), pp.969-973
- DOI
- 10.1249/MSS.0000000000000876
- PMID
- 26765634
- PMCID
- PMC4868651
- NLM abbreviation
- Med Sci Sports Exerc
- ISSN
- 0195-9131
- eISSN
- 1530-0315
- Language
- English
- Date published
- 06/2016
- Academic Unit
- Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
- Record Identifier
- 9984040446402771
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