Journal article
Outcomes of Cardiac Arrest with Valve Surgery Among Infective Endocarditis Patients: A United States National Cohort Study
Cardiovascular revascularization medicine, Vol.49, pp.49-53
04/01/2023
DOI: 10.1016/j.carrev.2022.11.004
PMID: 36460570
Abstract
Cardiac arrest can complicate infective endocarditis (IE) and is associated with significant in-hospital complications and mortality rates. We report the characteristics, outcomes, and readmission rates for IE patients with cardiac arrest in the United States.
We surveyed the Nationwide Readmission Database (NRD), a database designed to support national level readmission analyses, for patients admitted with IE and who had cardiac arrest during index admission between 2016 and 2019. Baseline demographics, comorbidities, surgical procedures, and outcomes were identified using their respective International Classification of Diseases (ICD) codes.
There were 663 index admissions (mean age 55.87 ± 17.21 years;34.2 % females) for IE with cardiac arrest in the study period, with an overall mortality rate of 55.3 %. Of these, 270 (40.7 %) had surgical procedures performed during the hospitalization encounter. In patients who had a surgical procedure, 72 (26.8 %) patients had in-hospital mortality while 293 (74.9 %) patients without surgical procedures had in-hospital mortality (p < 0.001). After coarsened matching for baseline characteristics, surgical valve procedures were less likely to be associated with mortality (OR = 0.09, 95%CI 0.04–0.24; p < 0.001). Among the 295 alive discharges associated with cardiac arrest, 76 (38.57 %) were readmitted within 30-days, with a mortality rate of 22 % noted for readmissions.
Among IE patients who had cardiac arrest, surgical procedures subgroup had low mortality despite having higher complication rates. However, due to chances of bias more randomized trials are needed evaluate the hypothesis.
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•Cardiac arrest among IE is associated with significant mortality, 55.3 %.•Patient who had valve surgery had less mortality, (mortality 26.8 % vs 74.9 %), however, there could selection bias.•About 38.57 % live discharges were readmitted within 30-days of discharge.•Mortality of 22 % was noted on 30-days of readmission.
Details
- Title: Subtitle
- Outcomes of Cardiac Arrest with Valve Surgery Among Infective Endocarditis Patients: A United States National Cohort Study
- Creators
- Tanveer Mir - Wayne State UniversityMohammed M. Uddin - Wayne State UniversityLayla Shanah - Wayne State UniversityTanveer Hussain - Wayne State UniversityTilachan Parajuli - Brookwood Baptist HealthObeid Shafi - University of Arkansas for Medical SciencesWaqas Ullah - Jefferson HospitalTanveer Rab - Emory UniversityMujeeb Sheikh - ProMedica Toledo HospitalEhab Eltahawy - University of Toledo
- Resource Type
- Journal article
- Publication Details
- Cardiovascular revascularization medicine, Vol.49, pp.49-53
- DOI
- 10.1016/j.carrev.2022.11.004
- PMID
- 36460570
- NLM abbreviation
- Cardiovasc Revasc Med
- ISSN
- 1553-8389
- eISSN
- 1878-0938
- Publisher
- Elsevier Inc
- Number of pages
- 5
- Language
- English
- Date published
- 04/01/2023
- Academic Unit
- Internal Medicine
- Record Identifier
- 9985014708802771
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