Outcomes toolbox for head and neck cancer research

Jolie Ringash; Lori J. Bernstein; David Cella; Jerilynn Logemann; Benjamin Movsas; Barbara Murphy; Andrea Trotti; Nancy Wells; Bevan Yueh; John Ridge

doi:10.1002/hed.23561

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Outcomes toolbox for head and neck cancer research

Journal article

Peer reviewed

Outcomes toolbox for head and neck cancer research

Jolie Ringash, Lori J. Bernstein, David Cella, Jerilynn Logemann, Benjamin Movsas, Barbara Murphy, Andrea Trotti, Nancy Wells, Bevan Yueh and John Ridge

Head & neck, Vol.37(3), pp.425-439

03/2015

DOI: 10.1002/hed.23561

PMID: 24318166

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Abstract

BackgroundClinical research in head and neck cancer traditionally focused on tumor control. As survival improves, it is increasingly recognized that the side-effects of multimodality treatment can be profound and enduring. Thus, clinical trials require patient-reported and functional outcomes. MethodsA subcommittee of the Previously Untreated, Locally Advanced (PULA) Task Force of the Head and Neck Steering Committee of the Coordinating Centre for Clinical Trials at the National Cancer Institute (NCI) was convened to identify a set of instruments suitable for widespread application in the conduct of clinical trials for head and neck cancer. ResultsBased on existing literature and expert opinion, 18 main areas of concern were identified. For each, measures suitable for use in multicenter clinical trials were recommended on the basis of validity, feasibility, and clinical acceptance. ConclusionSuitable instruments exist for most head and neck cancer concerns, but gaps require further development. Future efforts should be made to harmonize measurement across trials. (c) 2015 Wiley Periodicals, Inc. Head Neck 37: 425-439, 2015

Life Sciences & Biomedicine

Otorhinolaryngology

Science & Technology

Surgery

Details

Title: Subtitle: Outcomes toolbox for head and neck cancer research
Creators: Jolie Ringash - Princess Margaret Cancer Centre
Lori J. Bernstein - Princess Margaret Cancer Centre
David Cella - Northwestern University
Jerilynn Logemann - Northwestern University
Benjamin Movsas - Henry Ford Hospital
Barbara Murphy - Vanderbilt University
Andrea Trotti - Moffitt Cancer Center
Nancy Wells - Vanderbilt University
Bevan Yueh - University of Minnesota
John Ridge - Fox Chase Cancer Center
Resource Type: Journal article
Publication Details: Head & neck, Vol.37(3), pp.425-439
DOI: 10.1002/hed.23561
PMID: 24318166
NLM abbreviation: Head Neck
ISSN: 1043-3074
eISSN: 1097-0347
Publisher: Wiley
Number of pages: 15
Grant note: NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
Language: English
Date published: 03/2015
Academic Unit: Otolaryngology
Record Identifier: 9984966857002771

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