Overestimation of core infarct by computed tomography perfusion in the golden hour

Aldo A. Mendez; Darko Quispe-Orozco; Sudeepta Dandapat; Edgar A. Samaniego; Emily Tamadonfar; Cynthia B. Zevallos; Mudassir Farooqui; Colin P. Derdeyn; Santiago Ortega-Gutierrez

doi:10.4103/bc.bc_7_20

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Overestimation of core infarct by computed tomography perfusion in the golden hour

Journal article

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Overestimation of core infarct by computed tomography perfusion in the golden hour

Aldo A. Mendez, Darko Quispe-Orozco, Sudeepta Dandapat, Edgar A. Samaniego, Emily Tamadonfar, Cynthia B. Zevallos, Mudassir Farooqui, Colin P. Derdeyn and Santiago Ortega-Gutierrez

Brain circulation, Vol.6(3), pp.211-214

07/01/2020

DOI: 10.4103/bc.bc_7_20

PMCID: PMC7646387

PMID: 33210048

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646387View

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Abstract

A nonagenarian patient developed a right middle cerebral artery syndrome during recovery after a right internal carotid artery (ICA) balloon angioplasty. Emergent head computed tomography (CT) revealed no acute ischemic changes; CT angiography (CTA) and CT perfusion (CTP) demonstrated a right ICA occlusion with a large right hemispheric predicted core infarct by cerebral blood flow thresholds and minimal mismatch volume. She underwent complete reperfusion in <45 min from symptom onset. Magnetic resonance imaging brain obtained within 48 h showed a decreased infarct volume as that estimated by CTP. This case emphasizes the limitations of estimating the ischemic core with CTP in the golden hour with ultra-early reperfusion and suggests that CTP thresholds should not be used to exclude patients from treatment in the very early time window.

Clinical Neurology

Life Sciences & Biomedicine

Neurosciences

Neurosciences & Neurology

Science & Technology

Details

Title: Subtitle: Overestimation of core infarct by computed tomography perfusion in the golden hour
Creators: Aldo A. Mendez - University of Iowa Hospitals and Clinics
Darko Quispe-Orozco - University of Iowa
Sudeepta Dandapat - Univ Iowa Hosp & Clin, Dept Neurol, 200 Hawkins Dr,2155 Roy Carver Pavil, Iowa City, IA 52242 USA
Edgar A. Samaniego - University of Iowa
Emily Tamadonfar - University of Iowa Hospitals and Clinics
Cynthia B. Zevallos - University of Iowa
Mudassir Farooqui - University of Iowa
Colin P. Derdeyn - University of Iowa
Santiago Ortega-Gutierrez - University of Iowa Hospitals and Clinics
Resource Type: Journal article
Publication Details: Brain circulation, Vol.6(3), pp.211-214
DOI: 10.4103/bc.bc_7_20
PMID: 33210048
PMCID: PMC7646387
NLM abbreviation: Brain Circ
ISSN: 2394-8108
eISSN: 2455-4626
Publisher: Wolters Kluwer Medknow Publications
Number of pages: 6
Language: English
Date published: 07/01/2020
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984303442102771

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