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Overview of Plasma and Platelet Transfusions in Critically Ill Children
Journal article   Open access   Peer reviewed

Overview of Plasma and Platelet Transfusions in Critically Ill Children

Stacie Kahn, Madhuradhar Chegondi, Marianne E. Nellis and Oliver Karam
Frontiers in pediatrics, Vol.8, pp.601659-601659
11/13/2020
DOI: 10.3389/fped.2020.601659
PMCID: PMC7691248
PMID: 33282804
url
https://doi.org/10.3389/fped.2020.601659View
Published (Version of record) Open Access

Abstract

Critically ill children are a unique population who frequently receive plasma and platelet transfusions for both active bleeding and mitigation of bleeding risk. While these products are frequently administered, transfusion indications in this population remain unclear, and practice varies across institutions and providers. In this manuscript, we will outline the current evidence regarding plasma and platelet transfusions for hemostasis in the pediatric intensive care setting. For both products, we will describe the product composition, epidemiology, and product indications and discuss the potential risks and benefits involved with the transfusion. We will also discuss knowledge gaps and future areas of research.
Pediatrics critical ill children hemorrhage hemostasis plasma platelet transfusion

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