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Oxidant signalling in carcinogenesis: a commentary
Journal article   Peer reviewed

Oxidant signalling in carcinogenesis: a commentary

S S Deshpande and K Irani
Human & experimental toxicology, Vol.21(2), pp.63-64
02/2002
DOI: 10.1191/0960327102ht211oa
PMID: 12102497

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Abstract

It is becoming increasingly evident that reactive oxygen species (ROS) act at different stages of carcinogenesis, and thus play multiple roles in oncogenesis. In addition to being mutagenic and initiating tumors, ROS or carcinogens that result in ROS generation may affect tumor promotion and progression through varied effects on growth promoting, growth inhibitory, or apoptotic signaling pathways.
carcinogenesis intracellular signaling reactive oxygen species

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