Journal article
PC VIPR: A High-Speed 3D Phase-Contrast Method for Flow Quantification and High-Resolution Angiography
American journal of neuroradiology : AJNR, Vol.26(4), pp.743-749
04/01/2005
PMCID: PMC7977085
PMID: 15814915
Abstract
BACKGROUND AND PURPOSE:
Three-dimensional phase-contrast (3DPC) is limited by long imaging times, limited coverage, flow artifacts, and the need to perform multiple additional 2D examinations (2DPC) to measure flow. A highly undersampled 3D radial acquisition (isotropic-voxel radial projection imaging [PCVIPR]) makes it possible to increase the product of volume coverage and spatial resolution by a factor of 30 for the same imaging time as conventional Cartesian 3DPC. This provides anatomic information over a large volume with high isotropic resolution and permits retrospective measurement of average flow rates throughout the volume.
METHODS:
PCVIPR acquires a reference and three flow-encoded acquisitions for each VIPR projection. Complex difference images were formed by combining information from all flow directions. Following retrospective definition of planes perpendicular to selected vessels, volume flow rates were determined by using phase-difference information. The accuracy of average flow measurement was investigated in a phantom and in six volunteers. Anatomic PCVIPR images acquired in three patients and three volunteers by using a 384
3
matrix were compared with conventional Cartesian 3DPC.
RESULTS:
The flow validation produced
R
2
= 0.99
in vitro
and
R
2
= 0.97
in vivo
. PCVIPR produced minimal streak and pulsatile flow artifacts. PCVIPR produced far higher resolution and volume coverage in comparable imaging times. The highest acceleration factors relative to 3DPC were achieved by using gadolinium-contrast material. Ultimately, acceleration factors are limited by signal-to-noise ratio.
CONCLUSION:
PCVIPR rapidly provides isotropic high-resolution angiographic images and permits retrospective measurement of average flow rate throughout the volume without the need to prescribe multiple 2D acquisition planes.
Details
- Title: Subtitle
- PC VIPR: A High-Speed 3D Phase-Contrast Method for Flow Quantification and High-Resolution Angiography
- Creators
- Tianliang Gu - Department of Medical Physics, University of Wisconsin—Madison, Madison, WIFrank R. Korosec - Department of Medical Physics, University of Wisconsin—Madison, Madison, WI Department of Radiology, University of Wisconsin—Madison, Madison, WIWalter F. Block - Department of Medical Physics, University of Wisconsin—Madison, Madison, WI Department of Biomedical Engineering, University of Wisconsin—Madison, Madison, WISean B. Fain - Department of Radiology, University of Wisconsin—Madison, Madison, WIQuill Turk - Department of Radiology, University of Wisconsin—Madison, Madison, WIDarren Lum - Department of Radiology, University of Wisconsin—Madison, Madison, WIYong Zhou - General ElectricThomas M. Grist - Department of Medical Physics, University of Wisconsin—Madison, Madison, WI Department of Radiology, University of Wisconsin—Madison, Madison, WI Department of Biomedical Engineering, University of Wisconsin—Madison, Madison, WIVictor Haughton - Department of Radiology, University of Wisconsin—Madison, Madison, WICharles A. Mistretta - Department of Medical Physics, University of Wisconsin—Madison, Madison, WI Department of Radiology, University of Wisconsin—Madison, Madison, WI Department of Biomedical Engineering, University of Wisconsin—Madison, Madison, WI
- Resource Type
- Journal article
- Publication Details
- American journal of neuroradiology : AJNR, Vol.26(4), pp.743-749
- Publisher
- American Society of Neuroradiology
- PMID
- 15814915
- PMCID
- PMC7977085
- ISSN
- 0195-6108
- eISSN
- 1936-959X
- Language
- English
- Date published
- 04/01/2005
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Electrical and Computer Engineering; Health and Human Physiology
- Record Identifier
- 9984275058402771
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