Journal article
PROMOTING CONTINUOUS USE AS A STRATEGY FOR ACHIEVING ADHERENCE IN A TRIAL OF THE DIAPHRAGM WITH CANDIDATE MICROBICIDE
AIDS education and prevention, Vol.21(6), pp.512-525
12/01/2009
DOI: 10.1521/aeap.2009.21.6.512
PMID: 20030496
Abstract
Women need more choices for protection from HIV and other sexually transmitted infections (STIs). We conducted a randomized 4-week study in Madagascar in preparation for a Phase III randomized controlled trial (RCT) of the diaphragm with a candidate microbicide for STI prevention. All participants completed quantitative surveys; half participated in a qualitative interview. We advised women to wear the diaphragm at all times except for daily cleaning (rather than inserting it before intercourse). The objective of this analysis was to determine whether women who followed this "continuous use" approach more often used the diaphragm for 100% of sex acts as compared with other women. If so, this would support advising continuous diaphragm use in the upcoming RCT. To meet our objective, we analyzed qualitative data thematically, developed a measure of continuous diaphragm use based on qualitative data, and used multiple regression to evaluate the measure's association with adherence to diaphragm use during 100% of sex acts. Women who wore the diaphragm continuously had 4 times higher odds of reporting diaphragm use during 100% of sex acts (OR: 4.6, 95% CI: 1.2, 24.0). If the diaphragm proves effective against STI, continuous use may help women achieve high levels of protection.
Details
- Title: Subtitle
- PROMOTING CONTINUOUS USE AS A STRATEGY FOR ACHIEVING ADHERENCE IN A TRIAL OF THE DIAPHRAGM WITH CANDIDATE MICROBICIDE
- Creators
- Ana Penman-Aguilar - Centers for Disease Control and PreventionTeresa Swezey - Univ N Carolina, Chapel Hill, NC USAAbigail Norris Turner - Univ N Carolina, Chapel Hill, NC USAApril J. Bell - Ctr Dis Control & Prevent, Atlanta, GA USAFelasoa Noroseheno Ramiandrisoa - UNC Madagascar, Antananarivo, MadagascarJennifer Legardy-Williams - Ctr Dis Control & Prevent, Atlanta, GA USABodo Randrianasolo - UNC Madagascar, Antananarivo, MadagascarKathleen Van Damme - UNC Madagascar, Antananarivo, MadagascarJennifer Dulyx - Univ N Carolina, Chapel Hill, NC USAFrieda Behets - Univ N Carolina, Chapel Hill, NC USADenise J. Jamieson - Ctr Dis Control & Prevent, Atlanta, GA USA
- Resource Type
- Journal article
- Publication Details
- AIDS education and prevention, Vol.21(6), pp.512-525
- Publisher
- Guilford Publications Inc
- DOI
- 10.1521/aeap.2009.21.6.512
- PMID
- 20030496
- ISSN
- 0899-9546
- eISSN
- 1943-2755
- Number of pages
- 14
- Language
- English
- Date published
- 12/01/2009
- Academic Unit
- Obstetrics and Gynecology; VPMA - Administration
- Record Identifier
- 9984446437402771
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