Paediatric pancreatitis

John F Pohl; Aliye Uc

doi:10.1097/MOG.0000000000000197

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Journal article

Peer reviewed

Paediatric pancreatitis

John F Pohl and Aliye Uc

Current opinion in gastroenterology, Vol.31(5), pp.380-386

09/2015

DOI: 10.1097/MOG.0000000000000197

PMCID: PMC4732740

PMID: 26181572

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Abstract

The purpose of this review is to describe recent developments in paediatric pancreatitis and to discuss causes and current management. Although recent studies have estimated the annual incidence of paediatric acute pancreatitis approaching that of adults, there are no established guidelines about its diagnosis and treatment in children. Genetic and structural/congenital abnormalities are emerging as the primary risk factors for paediatric acute recurrent and chronic pancreatitis. Specifically, chronic pancreatitis is associated with a significant socioeconomic burden in children. Both medical and surgical therapies are proposed for paediatric chronic pancreatitis, but there is little evidence that they are beneficial. Acute recurrent and chronic pancreatitis create significant health issues in the paediatric population. Medical and surgical therapies exist to potentially treat these conditions, but the paediatric data are limited and the cohorts are small. A multidisciplinary and multicentre approach is necessary to better determine pancreatic disease processes and treatment options in children.

Enteral Nutrition - methods

Analgesics - therapeutic use

Pancreatitis, Chronic - etiology

Recurrence

Humans

Pancreatitis, Chronic - diagnosis

Risk Factors

Child, Preschool

Cholangiopancreatography, Endoscopic Retrograde

Pancreas - pathology

Treatment Outcome

Hospitalization

Pancreatitis, Chronic - psychology

Evidence-Based Medicine

Disease Progression

Incidence

Pancreas - abnormalities

Pain - psychology

Pain - drug therapy

Pancreatitis, Chronic - therapy

Quality of Life - psychology

Enteral Nutrition - psychology

Child

Practice Guidelines as Topic

Details

Title: Subtitle: Paediatric pancreatitis
Creators: John F Pohl - aDepartment of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah School of Medicine, Salt Lake City, Utah bDepartment of Pediatric Gastroenterology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
Aliye Uc
Resource Type: Journal article
Publication Details: Current opinion in gastroenterology, Vol.31(5), pp.380-386
DOI: 10.1097/MOG.0000000000000197
PMID: 26181572
PMCID: PMC4732740
NLM abbreviation: Curr Opin Gastroenterol
ISSN: 0267-1379
eISSN: 1531-7056
Publisher: United States
Grant note: R01 DK097820 / NIDDK NIH HHS DK096327 / NIDDK NIH HHS R21 DK096327 / NIDDK NIH HHS U01 DK108334 / NIDDK NIH HHS DK097820 / NIDDK NIH HHS
Language: English
Date published: 09/2015
Academic Unit: Stead Family Department of Pediatrics; Radiation Oncology; Gastroenterology, Hepatology, Pancreatology, and Nutrition
Record Identifier: 9984046910502771

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