Journal article
Pancreatic Pathophysiology in Cystic Fibrosis
The Journal of pathology, Vol.238(2), pp.311-320
01/2016
DOI: 10.1002/path.4634
PMCID: PMC4699289
PMID: 26365583
Abstract
The pancreas is one of the earliest- and most commonly- affected organs in patients with cystic fibrosis (CF). Studying the pathogenesis of pancreatic disease is limited in CF patients due to its early clinical onset, co-morbidities and lack of tissue samples from early phases of disease. In recent years, several new CF animal models have been developed that have advanced our understanding of both CF exocrine and endocrine pancreatic disease. Additionally, these models have helped us better define the influence of pancreatic lesions on CF disease progression in other organs such as the gastrointestinal tract and lung.
Details
- Title: Subtitle
- Pancreatic Pathophysiology in Cystic Fibrosis
- Creators
- Katherine N Gibson-Corley - Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242David K Meyerholz - Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242John F Engelhardt - Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242
- Resource Type
- Journal article
- Publication Details
- The Journal of pathology, Vol.238(2), pp.311-320
- DOI
- 10.1002/path.4634
- PMID
- 26365583
- PMCID
- PMC4699289
- ISSN
- 0022-3417
- eISSN
- 1096-9896
- Grant note
- DOI: 10.13039/100000050, name: National Heart, Lung, and Blood Institute, award: HL51670, HL091842, HL123482; DOI: 10.13039/100000062, name: National Institute of Diabetes and Digestive and Kidney Diseases, award: P30 DK054759, R24 DK096518; DOI: 10.13039/100000897, name: Cystic Fibrosis Foundation
- Language
- English
- Date published
- 01/2016
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Anatomy and Cell Biology; Pathology; Radiation Oncology; Internal Medicine; Ophthalmology and Visual Sciences
- Record Identifier
- 9984025344402771
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