Journal article
Paradoxical Prolactin Response to Growth Hormone-Releasing Hormone in a Patient with Hyperprolactinemia and Empty Sella
Endocrinologia japonica, Vol.38(2), pp.183-186
1991
DOI: 10.1507/endocrj1954.38.183
PMID: 1752237
Abstract
In a 30-year-old woman with amenorrhea due to hyperprolactinemia, serum PRL increased to twice the basal amount in response to growth hormone-releasing hormone (GHRH). Roentogenological studies revealed no pituitary adenoma but empty sella. Bromocriptine therapy normalized serum PRL and made the paradoxical response to GHRH disappear. The paradoxical response did not occur in any of eight other patients with hyperprolactinemia due to prolactinoma. Although this case is rare, GHRH stimulates PRL as well as GH release remarkably in some cases with hyperprolactinemia without a GH-producing tumor.
Details
- Title: Subtitle
- Paradoxical Prolactin Response to Growth Hormone-Releasing Hormone in a Patient with Hyperprolactinemia and Empty Sella
- Creators
- YUMI Imai - Toranomon HospitalTAEKO Shimizu - Toranomon HospitalSHINJI Sawano - Toranomon HospitalYASUNORI Ozawa - Toranomon HospitalTOMOJI Watanabe - Toranomon HospitalYOSHIMASA Shishiba - Toranomon Hospital
- Resource Type
- Journal article
- Publication Details
- Endocrinologia japonica, Vol.38(2), pp.183-186
- DOI
- 10.1507/endocrj1954.38.183
- PMID
- 1752237
- ISSN
- 0013-7219
- eISSN
- 2185-6370
- Language
- English
- Date published
- 1991
- Academic Unit
- Endocrinology and Metabolism; Internal Medicine
- Record Identifier
- 9984360046202771
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