Parkinson disease and driving: An evidence-based review

Alexander M CRIZZLE; Sherrilene CLASSEN; Ergun Y UC

doi:10.1212/WNL.0b013e3182749e95

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Parkinson disease and driving: An evidence-based review

Journal article

Open access

Peer reviewed

Parkinson disease and driving: An evidence-based review

Alexander M CRIZZLE, Sherrilene CLASSEN and Ergun Y UC

Neurology, Vol.79(20), pp.2067-2074

2012

DOI: 10.1212/WNL.0b013e3182749e95

PMCID: PMC3511919

PMID: 23150533

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https://europepmc.org/articles/pmc3511919View

Published (Version of record) Open Access

Abstract

The growing literature on driving in Parkinson disease (PD) has shown that driving is impaired in PD compared to healthy comparison drivers. PD is a complex neurodegenerative disorder leading to motor, cognitive, and visual impairments, all of which can affect fitness to drive. In this review, we examined studies of driving performance (on-road tests and simulators) in PD for outcome measures and their predictors. We searched through various databases and found 25 (of 99) primary studies, all published in English. Using the American Academy of Neurology criteria, a study class of evidence was assigned (I-IV, I indicating the highest level of evidence) and recommendations were made (Level A: predictive or not; B: probably predictive or not; C: possibly predictive or not; U: no recommendations). From available Class II and III studies, we identified various cognitive, visual, and motor measures that met different levels of evidence (usually Level B or C) with respect to predicting on-road and simulated driving performance. Class I studies reporting Level A recommendations for definitive predictors of driving performance in drivers with PD are needed by policy makers and clinicians to develop evidence-based guidelines.

Neurology

Biological and medical sciences

Medical sciences

Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases

Details

Title: Subtitle: Parkinson disease and driving: An evidence-based review
Creators: Alexander M CRIZZLE - Departments of Aging and Geriatric Research, University of Florida, Gainesville, United States
Sherrilene CLASSEN - Occupational Therapy, University of Florida, Gainesville, United States
Ergun Y UC - Department of Neurology, University of Iowa, United States
Resource Type: Journal article
Publication Details: Neurology, Vol.79(20), pp.2067-2074
DOI: 10.1212/WNL.0b013e3182749e95
PMID: 23150533
PMCID: PMC3511919
NLM abbreviation: Neurology
ISSN: 0028-3878
eISSN: 1526-632X
Publisher: Lippincott Williams & Wilkins; Hagerstown, MD
Language: English
Date published: 2012
Academic Unit: Neurology
Record Identifier: 9984020640902771

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