Journal article
Patient and caregiver quality of life in Huntington's disease
Movement disorders, Vol.23(5), pp.721-726
04/15/2008
DOI: 10.1002/mds.21920
PMCID: PMC3789516
PMID: 18175350
Abstract
Little is known about subjective perceptions of quality of life (QOL) in Huntington's disease (HD). The current study determined correlates of patient and caregiver QOL and assessed change over time. Participants were 22 patient-caregiver dyads, who rated QOL at baseline and 6 months later. Overall, patients' functional and cognitive impairment were significantly correlated with patient and caregiver QOL. Neuropsychiatric symptoms had differential impact on patient and caregiver QOL. Furthermore, when patients recalled their QOL about a previous time, their recall may have been negatively biased. Clinical implications of results are discussed. Future work is needed because subjective QOL is an important outcome measure in therapeutic trials. (c) 2008 Movement Disorder Society.
Details
- Title: Subtitle
- Patient and caregiver quality of life in Huntington's disease
- Creators
- Rebecca E. Ready - University of Massachusetts AmherstMelissa Mathews - University of Massachusetts AmherstAnne Leserman - University of IowaJane S. Paulsen - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Movement disorders, Vol.23(5), pp.721-726
- Publisher
- Wiley
- DOI
- 10.1002/mds.21920
- PMID
- 18175350
- PMCID
- PMC3789516
- ISSN
- 0885-3185
- eISSN
- 1531-8257
- Number of pages
- 6
- Grant note
- R01 NS040068 / NINDS NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) R01NS040068 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS)
- Language
- English
- Date published
- 04/15/2008
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984383296102771
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