Journal article
Patterns of Electrocardiographic Abnormalities in Children with Hypertrophic Cardiomyopathy
Pediatric cardiology, Vol.45(8), pp.1692-1701
12/2024
DOI: 10.1007/s00246-023-03252-4
PMID: 37684488
Abstract
Hypertrophic cardiomyopathy (HCM), a common cardiomyopathy in children, is an important cause of morbidity and mortality. Early recognition and appropriate management are important. An electrocardiogram (ECG) is often used as a screening tool in children to detect heart disease. The ECG patterns in children with HCM are not well described.ECGs collected from an international cohort of children, and adolescents (≤ 21 years) with HCM were reviewed. 482 ECGs met inclusion criteria. Age ranged from 1 day to 21 years, median 13 years. Of the 482 ECGs, 57 (12%) were normal. The most common abnormalities noted were left ventricular hypertrophy (LVH) in 108/482 (22%) and biventricular hypertrophy (BVH) in 116/482 (24%) Of the patients with LVH/BVH (n = 224), 135 (60%) also had a strain pattern (LVH in 83, BVH in 52). Isolated strain pattern (in the absence of criteria for hypertrophy) was seen in 43/482 (9%). Isolated pathologic Q waves were seen in 71/482 (15%). Pediatric HCM, 88% have an abnormal ECG. The most common ECG abnormalities were LVH or BVH with or without strain. Strain pattern without hypertrophy and a pathologic Q wave were present in a significant proportion (24%) of patients. Thus, a significant number of children with HCM have ECG abnormalities that are not typical for “hypertrophy”. The presence of the ECG abnormalities described above in a child should prompt further examination with an echocardiogram to rule out HCM.
Details
- Title: Subtitle
- Patterns of Electrocardiographic Abnormalities in Children with Hypertrophic Cardiomyopathy
- Creators
- Mayme MarshallAneeq MalikMaully ShahFrank A FishSusan P EtheridgePeter F AzizMark W RussellSvjetlana TismaAndreas PflaumerNarayanswami SreeramPeter KubusIan H LawMichal J KantochNaomi J KerteszMargaret StrieperChristopher C EricksonJeremy P MooreStephanie J NakanoHarinder R SinghPhilip ChangMitchell CohenAnne FournierMaria V IlinaFrank ZimmermannMichaela HorndaschWalter LiAnjan S BatraLeonardo LibermanRobert Hamilton - Hospital for Sick ChildrenChristopher M JansonShubhayan SanataniIlana ZeltserGeorge McDanielAndrew D BlaufoxJason M GarnreiterSeshadri Balaji
- Resource Type
- Journal article
- Publication Details
- Pediatric cardiology, Vol.45(8), pp.1692-1701
- DOI
- 10.1007/s00246-023-03252-4
- PMID
- 37684488
- NLM abbreviation
- Pediatr Cardiol
- ISSN
- 0172-0643
- eISSN
- 1432-1971
- Grant note
- name: Medtronic External Research Program, award: Protocol #1651
- Language
- English
- Electronic publication date
- 09/09/2023
- Date published
- 12/2024
- Academic Unit
- Cardiology; Stead Family Department of Pediatrics
- Record Identifier
- 9984464517202771
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