Journal article
Patterns of Yeast Infections and Antifungal Use in the First Trimester of Pregnancy: Findings from the Birth Defects Study to Evaluate Pregnancy exposureS, 2014-2019
Journal of women's health (Larchmont, N.Y. 2002), Vol.34(10), pp.1232-1239
10/01/2025
DOI: 10.1177/15409996251363394
PMID: 40719452
Abstract
Yeast infections are common during pregnancy. Understanding their current prevalence and corresponding treatments during pregnancy is important. We used data from a U.S. population-based retrospective study of recently pregnant people to describe patterns of first trimester maternal yeast infections and antifungal use.
Using a cohort of control participants from the Birth Defects Study to Evaluate Pregnancy exposureS, self-reports of first trimester yeast infections and antifungal use were collected via computer-assisted telephone interviews for births during 2014-2019. We described maternal characteristics and examined the prevalence of yeast infections and antifungal use overall and by study site and birth year. Tests for trend were used to evaluate changes over the study period.
After exclusions, there were 1,524 control participants included in our sample. First trimester yeast infections (9.8%) and antifungal use (8.6%) were common. More participants reported prescription (52.7%) than over-the-counter (45.0%) antifungals; most users reported a topical antifungal (72.5%). Prevalence of yeast infections and antifungal use increased modestly, but nonsignificantly, over the study period, ranging from 7.8% to 10.9% for yeast infections and 7.2% to 9.8% for antifungal use. Prevalence of topical and over-the-counter antifungals significantly increased over the study period; use of oral and prescription antifungals modestly decreased.
In our cohort, first trimester yeast infections and antifungal use were relatively common and modestly increased throughout the study period, although this trend was not significant. We observed significant increases for topical and over-the-counter antifungals. Additional research is needed to investigate the reasons behind these prevalence changes.
Details
- Title: Subtitle
- Patterns of Yeast Infections and Antifungal Use in the First Trimester of Pregnancy: Findings from the Birth Defects Study to Evaluate Pregnancy exposureS, 2014-2019
- Creators
- Eleni A Papadopoulos - New York State Department of HealthMeredith M Howley - New York State Department of HealthSarah C Fisher - New York State Department of HealthMartha M Werler - Boston UniversityPaul A Romitti - University of IowaMarilyn L Browne - University at Albany, State University of New YorkBirth Defects Study to Evaluate Pregnancy exposures
- Resource Type
- Journal article
- Publication Details
- Journal of women's health (Larchmont, N.Y. 2002), Vol.34(10), pp.1232-1239
- DOI
- 10.1177/15409996251363394
- PMID
- 40719452
- NLM abbreviation
- J Womens Health (Larchmt)
- ISSN
- 1540-9996
- eISSN
- 1931-843X
- Publisher
- MARY ANN LIEBERT, INC
- Grant note
- University at Albany, State University of New York, School of Public Health
Portions of the article were previously published in the following thesis: Student name: Eleni A. Papadopoulos. Degree earned: PhD in Epidemiology. Date: August 2022. Granting institution: University at Albany, State University of New York, School of Public Health. Website/DOI: https://doi.org/10.54014/WC7E-X8F3
- Language
- English
- Electronic publication date
- 07/28/2025
- Date published
- 10/01/2025
- Academic Unit
- Epidemiology; Biostatistics
- Record Identifier
- 9984927207502771
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