Journal article
Patterns of antidepressant medication use among pregnant women in a United States population
Journal of clinical pharmacology, Vol.51(2), pp.264-270
02/2011
DOI: 10.1177/0091270010373928
PMID: 20663997
Abstract
This article describes the pattern of reported antidepressant use around the time of pregnancy in a population-based sample of women who delivered live-born babies without birth defects. Data were used from the National Birth Defects Prevention Study, an ongoing case-control study of risk factors for birth defects covering 10 US states. Mothers of live-born infants without birth defects (controls) born between 1998 and 2005 were randomly selected from each site. Information on the mother's characteristics and exposure to antidepressants was collected via a standardized telephone interview. Among 6582 mothers included in the study, 298 (4.5%) reported use of an antidepressant in the period of 3 months before through the end of pregnancy. Use of selective serotonin-reuptake inhibitors was reported most often (3.8%), followed by bupropion (0.7%). A statistically significant decline was observed, from 3.1% to 2.3% (P < .001), in reported use of antidepressants between the first and second month after conception. The frequency of reported antidepressant use at any time during pregnancy increased from 2.5% in 1998 to 8.1% in 2005 (P < .001) in 4 states. The findings show an increase in reported antidepressant use over a 9-year period and a substantial decrease in use around the usual time of pregnancy recognition.
Details
- Title: Subtitle
- Patterns of antidepressant medication use among pregnant women in a United States population
- Creators
- Sura Alwan - National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-86, Atlanta, GA 30333, USAJennita ReefhuisSonja A RasmussenJan M FriedmanNational Birth Defects Prevention Study
- Contributors
- Paul A Romitti (Contributor) - University of Iowa, Epidemiology
- Resource Type
- Journal article
- Publication Details
- Journal of clinical pharmacology, Vol.51(2), pp.264-270
- DOI
- 10.1177/0091270010373928
- PMID
- 20663997
- ISSN
- 0091-2700
- eISSN
- 1552-4604
- Language
- English
- Date published
- 02/2011
- Academic Unit
- Epidemiology; Biostatistics
- Record Identifier
- 9984214785502771
Metrics
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