Journal article
Pediatric Odontogenic and Maxillofacial Bone Pathology: A Global Analysis
The Journal of craniofacial surgery, Vol.33(3), pp.870-874
05/01/2022
DOI: 10.1097/SCS.0000000000008201
Abstract
BACKGROUNDAlthough pathology in the maxillary and mandibular bones is rare in young patients, the differential diagnosis is broad. The World Health Organization (WHO) updated its classification of maxillofacial bone pathology in 2017. Using these updated guidelines, a systematic review of common maxillofacial bone lesions in the pediatric population was performed. METHODSA PubMed search was conducted capturing English language articles from inception to July 2020. Thirty-one articles were identified that described the frequency of maxillofacial bone pathology. Data were extracted and organized using the WHO 2017 classification of odontogenic and maxillofacial bone tumors. Prevalence data were analyzed among diagnostic categories and geographical regions. The SAS version 9.4 was used to complete statistical analyses. RESULTSThe articles included patients from birth to a maximum age of 14 to 19 years. The most common odontogenic cysts included radicular cyst (42.7%) and dentigerous cyst (39.0%) followed by odontogenic keratocyst (15.0%). Among odontogenic bone tumors, odontoma (49.3%) was most common followed by ameloblastoma (29.1%). The most common nonodontogenic bone tumor was fibrous dysplasia (42.4%), and the most common malignant bone tumor was osteosarcoma (75.0%). Significant variations were found by geographic region, with dentigerous cyst more common than radicular cyst, and ameloblastoma more common than odontoma in African and Asian countries (P < 0.0001). CONCLUSIONSThis systematic review uses the WHO 2017 guidelines to classify common odontogenic and nonodontogenic maxillofacial bone lesions around the world. Pathogenesis, presentation, and available treatment options for the most common maxillofacial bone lesions are reviewed.
Details
- Title: Subtitle
- Pediatric Odontogenic and Maxillofacial Bone Pathology: A Global Analysis
- Creators
- Ravi K Garg - University of Kansas Medical CenterMichaela K O'ConnorDavid A SterlingLaya JacobJeffrey A HammoudehBrian T Andrews
- Resource Type
- Journal article
- Publication Details
- The Journal of craniofacial surgery, Vol.33(3), pp.870-874
- DOI
- 10.1097/SCS.0000000000008201
- ISSN
- 1049-2275
- eISSN
- 1536-3732
- Language
- English
- Date published
- 05/01/2022
- Academic Unit
- Craniofacial Anomalies Research Center; Neurosurgery; Otolaryngology
- Record Identifier
- 9984366371202771
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